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GWAS Study

Resistance to TST/IGRA conversion in Uganda: Heritability and Genome-Wide Association Study.

McHenry ML, Benchek P, Malone L et al.

34871961 PubMed ID
GWAS Study Type
263 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

MM
McHenry ML
BP
Benchek P
ML
Malone L
NM
Nsereko M
MH
Mayanja-Kizza H
BW
Boom WH
WS
Williams SM
HT
Hawn TR
SC
Stein CM
Chapter II

Abstract

Summary of the research findings

Pulmonary tuberculosis (TB) is one of the most deadly pathogens on earth. However, the majority of people have resistance to active disease. Further, some individuals, termed resisters (RSTRs), do not develop traditional latent tuberculosis (LTBI). The RSTR phenotype is important for understanding pathogenesis and preventing TB. The host genetic underpinnings of RSTR are largely understudied.

74 African ancestry cases, 189 African ancestry controls

Chapter III

Study Statistics

Key metrics and study information

263
Total Participants
GWAS
Study Type
No
Replicated
African unspecified
Ancestry
Uganda
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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