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GWAS Study

Mendelian Randomization Analysis Reveals No Causal Relationship Between Nonalcoholic Fatty Liver Disease and Severe COVID-19.

Li J, Tian A, Zhu H et al.

35124268 PubMed ID
GWAS Study Type
429963 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

LJ
Li J
TA
Tian A
ZH
Zhu H
CL
Chen L
WJ
Wen J
LW
Liu W
CP
Chen P
Chapter II

Abstract

Summary of the research findings

Background & aims: The coronavirus disease 2019 (COVID-19) pandemic has witnessed more than 4.5 million deaths as of the time of writing. Whether nonalcoholic fatty liver disease (NAFLD) increases the risk for severe COVID-19 remains unclear. We sought to address this question using 2-sample Mendelian randomization (TSMR) analysis approaches in large cohorts.

3,711 European ancestry cases, 426,252 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

429963
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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