Identification of genetic loci simultaneously associated with multiple cardiometabolic traits.
Wood AC, Arora A, Newell M et al.
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Abstract
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Background and aims: Cardiometabolic disorders (CMD) arise from a constellation of features such as increased adiposity, hyperlipidemia, hypertension and compromised glucose control. Many genetic loci have shown associations with individual CMD-related traits, but no investigations have focused on simultaneously identifying loci showing associations across all domains. We therefore sought to identify loci associated with risk across seven continuous CMD-related traits.
453,413 European ancestry individuals
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