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GWAS Study

GWAS in people of Middle Eastern descent reveals a locus protective of kidney function-a cross-sectional study.

Mohamed SA, Fernadez-Tajes J, Franks PW et al.

35227251 PubMed ID
GWAS Study Type
1201 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

MS
Mohamed SA
FJ
Fernadez-Tajes J
FP
Franks PW
BL
Bennet L
Chapter II

Abstract

Summary of the research findings

Type 2 diabetes is one of the leading causes of chronic kidney failure, which increases globally and represents a significant threat to public health. People from the Middle East represent one of the largest immigrant groups in Europe today. Despite poor glucose regulation and high risk for early-onset insulin-deficient type 2 diabetes, they have better kidney function and lower rates of all-cause and cardiovascular-specific mortality compared with people of European ancestry. Here, we assessed the genetic basis of estimated glomerular filtration rate (eGFR) and other metabolic traits in people of Iraqi ancestry living in southern Sweden.

1,201 Iraqi ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

1201
Total Participants
GWAS
Study Type
No
Replicated
Greater Middle Eastern (Middle Eastern, North African or Persian)
Ancestry
Sweden
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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