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GWAS Study

A Genome-Wide Association Study and Machine-Learning Algorithm Analysis on the Prediction of Facial Phenotypes by Genotypes in Korean Women.

Yoo HY, Lee KC, Woo JE et al.

35313536 PubMed ID
GWAS Study Type
730 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

YH
Yoo HY
LK
Lee KC
WJ
Woo JE
PS
Park SH
LS
Lee S
JJ
Joo J
BJ
Bae JS
KH
Kwon HJ
PB
Park BJ
Chapter II

Abstract

Summary of the research findings

Purpose: Changes in facial appearance are affected by various intrinsic and extrinsic factors, which vary from person to person. Therefore, each person needs to determine their skin condition accurately to care for their skin accordingly. Recently, genetic identification by skin-related phenotypes has become possible using genome-wide association studies (GWAS) and machine-learning algorithms. However, because most GWAS have focused on populations with American or European skin pigmentation, large-scale GWAS are needed for Asian populations. This study aimed to evaluate the correlation of facial phenotypes with candidate single-nucleotide polymorphisms (SNPs) to predict phenotype from genotype using machine learning.

730 Korean ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

730
Total Participants
GWAS
Study Type
No
Replicated
East Asian
Ancestry
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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