Identification and functional validation of HLA-C as a potential gene involved in colorectal cancer in the Korean population.
Lim EB, Oh HS, Kim KC et al.
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Colorectal cancer (CRC) is the third most common cancer worldwide and is influenced by environmental and genetic factors. Although numerous genetic loci for CRC have been identified, the overall understanding of the genetic factors is yet to be elucidated. We sought to discover new genes involved in CRC applying genetic association analysis and functional study.
194 Korean ancestry cases, 600 Korean ancestry controls
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