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GWAS Study

Pharmacogenetics of dolutegravir plasma exposure among Southern Africans living with HIV.

Cindi Z, Kawuma AN, Maartens G et al.

35512135 PubMed ID
GWAS Study Type
284 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

CZ
Cindi Z
KA
Kawuma AN
MG
Maartens G
BY
Bradford Y
VF
Venter F
SS
Sokhela S
CN
Chandiwana N
WR
Wasmann RE
DP
Denti P
WL
Wiesner L
RM
Ritchie MD
HD
Haas DW
SP
Sinxadi P
Chapter II

Abstract

Summary of the research findings

Dolutegravir is a component of preferred antiretroviral therapy (ART) regimens. We characterized the pharmacogenetics of dolutegravir exposure after ART initiation in the ADVANCE trial in South Africa.

284 Black individuals

Chapter III

Study Statistics

Key metrics and study information

284
Total Participants
GWAS
Study Type
No
Replicated
African unspecified
Ancestry
South Africa
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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