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GWAS Study

Identification of Two Genetic Loci Associated with Leukopenia after Chemotherapy in Breast Cancer Patients.

Fasching PA, Liu D, Scully S et al.

35653140 PubMed ID
GWAS Study Type
3322 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

FP
Fasching PA
LD
Liu D
SS
Scully S
IJ
Ingle JN
LP
Lyra PC
RB
Rack B
HA
Hein A
EA
Ekici AB
RA
Reis A
SA
Schneeweiss A
TH
Tesch H
FT
Fehm TN
HG
Heinrich G
BM
Beckmann MW
RM
Ruebner M
HH
Huebner H
LD
Lambrechts D
ME
Madden E
SJ
Shen J
RJ
Romm J
DK
Doheny K
JG
Jenkins GD
CE
Carlson EE
LL
Li L
FB
Fridley BL
CJ
Cunningham JM
JW
Janni W
MA
Monteiro ANA
SD
Schaid DJ
HL
Häberle L
WR
Weinshilboum RM
WL
Wang L
Chapter II

Abstract

Summary of the research findings

Purpose: To identify molecular predictors of grade 3/4 neutropenic or leukopenic events (NLE) after chemotherapy using a genome-wide association study (GWAS).

1,679 European ancestry cases with events, 1,643 European ancestry cases without events

Chapter III

Study Statistics

Key metrics and study information

3322
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
Germany
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

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