Polygenic risk score for ACE-inhibitor-associated cough based on the discovery of new genetic loci.
Ghouse J, Tragante V, Muhammad A et al.
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Abstract
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Aims: To search for sequence variants associated with ACEi discontinuation and to test their association with ACEi-associated adverse drug reactions (ADRs).
33,959 European ancestry cases who discontinued ACEi, 44,041 European ancestry controls who continued ACEi treatment
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