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GWAS Study

Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women.

Chung J, Das A, Sun X et al.

35770850 PubMed ID
GWAS Study Type
10340 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

CJ
Chung J
DA
Das A
SX
Sun X
SD
Sobreira DR
LY
Leung YY
IC
Igartua C
MS
Mozaffari S
CY
Chou YF
TS
Thiagalingam S
MJ
Mez J
ZX
Zhang X
JG
Jun GR
ST
Stein TD
KB
Kunkle BW
ME
Martin ER
PM
Pericak-Vance MA
MR
Mayeux R
HJ
Haines JL
SG
Schellenberg GD
NM
Nobrega MA
LK
Lunetta KL
PJ
Pinto JM
WL
Wang LS
OC
Ober C
FL
Farrer LA
Chapter II

Abstract

Summary of the research findings

Introduction: Variants in the tau gene (MAPT) region are associated with breast cancer in women and Alzheimer's disease (AD) among persons lacking apolipoprotein E ε4 (ε4-).

3,399 European ancestry female cases, 6,905 European ancestry female controls

Chapter III

Study Statistics

Key metrics and study information

10340
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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