Preliminary genome wide screening identifies new variants associated with coronary artery disease in Indian population.
Bhat KG, Guleria VS, J RK et al.
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Abstract
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Aim: Coronary artery disease (CAD) is a major health problem in developed and developing nations. Development of CAD involves a complex interaction between genetics and lifestyle factors. Individuals with high-risk genetic predisposition along with poor lifestyle are more inclined to the development of CAD. Advancement in genotyping technologies and increase in genome wide studies has provided a platform to identify new risk factors associated with CAD and associated complexities.
76 Indian ancestry cases, 77 Indian ancestry controls
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