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GWAS Study

Sex-Specific Genetic and Transcriptomic Liability to Neuroticism.

Wendt FR, Pathak GA, Singh K et al.

36244801 PubMed ID
GWAS Study Type
129229 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

WF
Wendt FR
PG
Pathak GA
SK
Singh K
SM
Stein MB
KK
Koenen KC
KJ
Krystal JH
GJ
Gelernter J
DL
Davis LK
PR
Polimanti R
Chapter II

Abstract

Summary of the research findings

The presentation, etiology, and relative risk of psychiatric disorders are strongly influenced by biological sex. Neuroticism is a transdiagnostic feature of psychiatric disorders displaying prominent sex differences. We performed genome-wide association studies of neuroticism separately in males and females to identify sex-specific genetic and transcriptomic profiles.

129,229 European ancestry men

Chapter III

Study Statistics

Key metrics and study information

129229
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.K.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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