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GWAS Study

A genome-wide association study identifying single nucleotide polymorphisms in the <i>PPFIBP2</i> gene was predictive for interstitial lung disease in rheumatoid arthritis patients.

Hayashi S, Matsubara T, Fukuda K et al.

36382269 PubMed ID
GWAS Study Type
306 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

HS
Hayashi S
MT
Matsubara T
FK
Fukuda K
MT
Maeda T
FK
Funahashi K
HM
Hashimoto M
TY
Takashima Y
KK
Kikuchi K
FM
Fujita M
MT
Matsumoto T
KR
Kuroda R
Chapter II

Abstract

Summary of the research findings

Objective: Genetic polymorphisms might serve as useful prognostic markers for the timely diagnosis of RA. The purpose of this study was to identify genomic factors predictive of the occurrence of interstitial lung disease (ILD) in RA by performing a genome-wide association study of genetic variants, including single nucleotide polymorphisms (SNPs).

57 Japanese ancestry cases, 249 Japanese ancestry controls

Chapter III

Study Statistics

Key metrics and study information

306
Total Participants
GWAS
Study Type
No
Replicated
East Asian
Ancestry
Japan
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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