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GWAS Study

Mapping gene by early life stress interactions on child subcortical brain structures: A genome-wide prospective study.

Bolhuis K, Mulder RH, de Mol CL et al.

36777645 PubMed ID
GWAS Study Type
1049 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

BK
Bolhuis K
MR
Mulder RH
DM
de Mol CL
DS
Defina S
WV
Warrier V
WT
White T
TH
Tiemeier H
MR
Muetzel RL
CC
Cecil CAM
Chapter II

Abstract

Summary of the research findings

Although it is well-established that both genetics and the environment influence brain development, they are typically examined separately. Here, we aimed to prospectively investigate the interactive effects of genetic variants-from a genome-wide approach-and early life stress (ELS) on child subcortical brain structures, and their association with subsequent mental health problems.

1,049 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

1049
Total Participants
GWAS
Study Type
Yes
Replicated
10,749 European or unknown ancestry individuals
Replication Participants
European, NR
Ancestry
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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