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GWAS Study

Lifetime risk and genetic predisposition to post-traumatic OA of the knee in the UK Biobank.

Hollis B, Chatzigeorgiou C, Southam L et al.

37247657 PubMed ID
GWAS Study Type
3074 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

HB
Hollis B
CC
Chatzigeorgiou C
SL
Southam L
HK
Hatzikotoulas K
KS
Kluzek S
WA
Williams A
ZE
Zeggini E
JL
Jostins-Dean L
WF
Watt FE
Chapter II

Abstract

Summary of the research findings

Objective: Acute knee injury is associated with post-traumatic OA (PTOA). Very little is known about the genome-wide associations of PTOA when compared with idiopathic OA (iOA). Our objective was to describe the development of knee OA after a knee injury and its genetic associations in UK Biobank (UKB).

377 European ancestry post-injury cases, 2,697 European ancestry post-injury controls

Chapter III

Study Statistics

Key metrics and study information

3074
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.K.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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