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GWAS Study

Extended genome-wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry.

Ray NR, Kunkle BW, Hamilton-Nelson K et al.

38958117 PubMed ID
GWAS Study Type
9168 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

RN
Ray NR
KB
Kunkle BW
HK
Hamilton-Nelson K
KJ
Kurup JT
RF
Rajabli F
QM
Qiao M
VB
Vardarajan BN
CM
Cosacak MI
KC
Kizil C
JM
Jean-Francois M
CM
Cuccaro M
RD
Reyes-Dumeyer D
CL
Cantwell L
KA
Kuzma A
VJ
Vance JM
GS
Gao S
HH
Hendrie HC
BO
Baiyewu O
OA
Ogunniyi A
AR
Akinyemi RO
LW
Lee WP
ME
Martin ER
WL
Wang LS
BG
Beecham GW
BW
Bush WS
XW
Xu W
JF
Jin F
WL
Wang L
FL
Farrer LA
HJ
Haines JL
BG
Byrd GS
SG
Schellenberg GD
MR
Mayeux R
PM
Pericak-Vance MA
RC
Reitz C
Chapter II

Abstract

Summary of the research findings

Introduction: Despite a two-fold risk, individuals of African ancestry have been underrepresented in Alzheimer's disease (AD) genomics efforts.

77 African ancestry cases, 628 African ancestry controls, 2,826 African American cases, 5,637 African American controls

Chapter III

Study Statistics

Key metrics and study information

9168
Total Participants
GWAS
Study Type
No
Replicated
Sub-Saharan African, African American or Afro-Caribbean
Ancestry
Nigeria, U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.