A large-scale genome-wide association study on female genital tract polyps highlights role of DNA repair, cell proliferation, and cell growth.
Pathare ADS, Džigurski J, Pujol-Gualdo N et al.
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Abstract
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Study question: Can a large-scale genome-wide association study (GWAS) meta-analysis identify genomic risk loci and likely involved genes for female genital tract (FGT) polyps, provide insights into the biological mechanism underlying their development, and inform of potential overlap with other traits, including endometrial cancer?
36,984 European ancestry cases, 420,993 European ancestry controls
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