Genome-wide association study of susceptibility to acute respiratory distress syndrome.
Guillen-Guio B, Suarez-Pajes E, Tosco-Herrera E et al.
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Abstract
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Acute respiratory distress syndrome (ARDS) is a severe inflammatory process of the lung, often due to sepsis, and poses significant mortality burden in intensive care units. Here we conducted a genome-wide association study (GWAS) of ARDS to identify genetic risk loci that can help guide the development of new therapeutic options.
395 European ancestry cases, 1,150 European ancestry controls, 321 European, African, Asian or admixed ancestry cases, 3,249 European, African, Asian or admixed ancestry controls
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