Active: Anxiety disorder Clear all

GWAS 2024-09-20

Identification of novel genomic loci for anxiety symptoms and extensive genetic overlap with psychiatric disorders.

Tesfaye M, Jaholkowski P et al.

Psychiatry Clin Neurosci

Aims: Anxiety disorders are prevalent and anxiety symptoms (ANX) co-occur with many psychiatric diso...

Anxiety score

126569

Participants

N/A

Studies

Details PubMed

GWAS 2024-09-18

Gene discovery and biological insights into anxiety disorders from a large-scale multi-ancestry genome-wide association study.

Friligkou E, Løkhammer S et al.

Nat Genet

We leveraged information from more than 1.2 million participants, including 97,383 cases, to investi...

Anxiety disorder

1096458

Participants

N/A

Studies

Details PubMed

GWAS 2024-07-10

Investigating the impact of poverty on mental illness in the UK Biobank using Mendelian randomization.

Marchi M, Alkema A et al.

Nat Hum Behav

It is unclear whether poverty and mental illness are causally related. Using UK Biobank and Psychiat...

Poverty (general factor)

453689

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-09

Genome-wide meta-analysis, functional genomics and integrative analyses implicate new risk genes and therapeutic targets for anxiety disorders.

Li W, Chen R et al.

Nat Hum Behav

Anxiety disorders are the most prevalent mental disorders. However, the genetic etiology of anxiety ...

Anxiety disorder

475216

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-31

Testing associations between human anxiety and genes previously implicated by mouse anxiety models.

Brasher MS, Mize TJ et al.

Genes Brain Behav

Anxiety disorders are common and can be debilitating, with effective treatments remaining hampered b...

Feeling anxious - several or more days in the last two weeks

138905

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-13

Genetic examination of the Mood Disorder Questionnaire and its relationship with bipolar disorder.

Mundy J, Hübel C et al.

Am J Med Genet B Neuropsychiatr Genet

The Mood Disorder Questionnaire (MDQ) is a common screening tool for bipolar disorder that assesses ...

Concurrent manic symptoms in manic depressive disorder and/or anxiety disorders (sum score)

11568

Participants

N/A

Studies

Details PubMed

GWAS 2022-12-23

The first genome-wide association study of internet addiction; Revealed substantial shared risk factors with neurodevelopmental psychiatric disorders.

Haghighatfard A, Ghaderi AH et al.

Res Dev Disabil

Internet addiction disorder (IAD) is listed as a disorder requiring further studies in the diagnosti...

Internet addiction disorder

34520

Participants

N/A

Studies

Details PubMed

GWAS 2022-02-18

Using phenotype risk scores to enhance gene discovery for generalized anxiety disorder and posttraumatic stress disorder.

Wendt FR, Pathak GA et al.

Mol Psychiatry

UK Biobank (UKB) is a key contributor in mental health genome-wide association studies (GWAS) but on...

Generalized anxiety disorder (mental health questionnaire or predicted)

489579

Participants

N/A

Studies

Details PubMed

GWAS 2021-12-08

Biology of Perseverative Negative Thinking: The Role of Timing and Folate Intake.

Eszlari N, Bruncsics B et al.

Nutrients

Past-oriented rumination and future-oriented worry are two aspects of perseverative negative thinkin...

Rumination in optimal folate intake

61983

Participants

N/A

Studies

Details PubMed

GWAS 2021-11-05

Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders.

Eijsbouts C, Zheng T et al.

Nat Genet

Irritable bowel syndrome (IBS) results from disordered brain-gut interactions. Identifying susceptib...

Irritable bowel syndrome

Replicated

2075908

Participants

N/A

Studies

Details PubMed

GWAS 2021-06-29

Genome-wide association study of stimulant dependence.

Cox J, Sherva R et al.

Transl Psychiatry

Stimulant dependence is heritable, but specific genetic factors underlying the trait have not been i...

Stimulant dependence

Replicated

22416

Participants

N/A

Studies

Details PubMed

GWAS 2020-01-07

Reproducible Genetic Risk Loci for Anxiety: Results From ∼200,000 Participants in the Million Veteran Program.

Levey DF, Gelernter J et al.

Am J Psychiatry

Objective: Anxiety disorders are common and often disabling. The goal of this study was to examine t...

Anxiety

199611

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Identification of novel genomic loci for anxiety symptoms and extensive genetic overlap with psychiatric disorders.

Tesfaye M, Jaholkowski P et al.

Psychiatry Clin Neurosci

Anxiety score

2024-09-20

Gene discovery and biological insights into anxiety disorders from a large-scale multi-ancestry genome-wide association study.

Friligkou E, Løkhammer S et al.

Nat Genet

Anxiety disorder

2024-09-18

Investigating the impact of poverty on mental illness in the UK Biobank using Mendelian randomization.

Marchi M, Alkema A et al.

Nat Hum Behav

Poverty (general factor)

2024-07-10

Genome-wide meta-analysis, functional genomics and integrative analyses implicate new risk genes and therapeutic targets for anxiety disorders.

Li W, Chen R et al.

Nat Hum Behav

Anxiety disorder

2023-11-09

Testing associations between human anxiety and genes previously implicated by mouse anxiety models.

Brasher MS, Mize TJ et al.

Genes Brain Behav

Feeling anxious - several or more days in the last two weeks

2023-05-31

Genetic examination of the Mood Disorder Questionnaire and its relationship with bipolar disorder.

Mundy J, Hübel C et al.

Am J Med Genet B Neuropsychiatr Genet

Concurrent manic symptoms in manic depressive disorder and/or anxiety disorders (sum score)

2023-05-13

The first genome-wide association study of internet addiction; Revealed substantial shared risk factors with neurodevelopmental psychiatric disorders.

Haghighatfard A, Ghaderi AH et al.

Res Dev Disabil

Internet addiction disorder

2022-12-23

Using phenotype risk scores to enhance gene discovery for generalized anxiety disorder and posttraumatic stress disorder.

Wendt FR, Pathak GA et al.

Mol Psychiatry

Generalized anxiety disorder (mental health questionnaire or predicted)

2022-02-18

Biology of Perseverative Negative Thinking: The Role of Timing and Folate Intake.

Eszlari N, Bruncsics B et al.

Nutrients

Rumination in optimal folate intake

2021-12-08

Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders.

Eijsbouts C, Zheng T et al.

Nat Genet

Irritable bowel syndrome

2021-11-05

Genome-wide association study of stimulant dependence.

Cox J, Sherva R et al.

Transl Psychiatry

Stimulant dependence

2021-06-29

Reproducible Genetic Risk Loci for Anxiety: Results From ∼200,000 Participants in the Million Veteran Program.

Levey DF, Gelernter J et al.

Am J Psychiatry

Anxiety

2020-01-07