Active: Bipolar disorder Clear all

GWAS 2025-11-04

The Genetic Architecture of the Human Corpus Callosum and its Subregions.

Bhatt RR, Gadewar SP et al.

Nat Commun

The corpus callosum (CC) is the largest set of white matter fibers connecting the two hemispheres of...

Corpus callosum total area

Replicated

51450

Participants

N/A

Studies

Details PubMed

GWAS 2024-09-18

Gene discovery and biological insights into anxiety disorders from a large-scale multi-ancestry genome-wide association study.

Friligkou E, Løkhammer S et al.

Nat Genet

We leveraged information from more than 1.2 million participants, including 97,383 cases, to investi...

Anxiety disorder

1096458

Participants

N/A

Studies

Details PubMed

GWAS 2024-07-10

Investigating the impact of poverty on mental illness in the UK Biobank using Mendelian randomization.

Marchi M, Alkema A et al.

Nat Hum Behav

It is unclear whether poverty and mental illness are causally related. Using UK Biobank and Psychiat...

Poverty (general factor)

453689

Participants

N/A

Studies

Details PubMed

GWAS 2024-06-11

Shared genetic effect of kidney function on bipolar and major depressive disorders: a large-scale genome-wide cross-trait analysis.

Yu S, Lin Y et al.

Hum Genomics

Epidemiological studies have revealed a significant association between impaired kidney function and...

Bipolar disorder or blood urea nitrogen levels (MTAG)

904388

Participants

N/A

Studies

Details PubMed

GWAS 2024-04-01

Genome-wide association study of early-onset and late-onset postpartum depression: the IGEDEPP prospective study.

Tebeka S, Gloaguen E et al.

Eur Psychiatry

Postpartum depression (PPD) appears at two peak periods: early-onset prior to 2 months after deliver...

Early-onset postpartum depression

1438

Participants

N/A

Studies

Details PubMed

GWAS 2024-02-26

Genetic risk for hospitalization of African American patients with severe mental illness reveals HLA loci.

Lori A, Pearce BD et al.

Front Psychiatry

Mood disorders such as major depressive and bipolar disorders, along with posttraumatic stress disor...

Hospitalization rate in serious mental illnesses

5157

Participants

N/A

Studies

Details PubMed

GWAS 2024-02-13

Pharmacogenomic overlap between antidepressant treatment response in major depression & antidepressant associated treatment emergent mania in bipolar disorder.

Nuñez NA, Coombes BJ et al.

Transl Psychiatry

There is increasing interest in individualizing treatment selection for more than 25 regulatory appr...

Antidepressant-associated treatment emergent mania in BD

861

Participants

N/A

Studies

Details PubMed

GWAS 2023-12-26

Genetic correlation, shared loci, but no causality between bipolar disorder and inflammatory bowel disease: A genome-wide pleiotropic analysis.

Wang BR, Wang J et al.

J Affect Disord

Background and aims: The comorbidity between bipolar disorder (BD) and inflammatory bowel disease (I...

Bipolar disorder or inflammatory bowel disease (MTAG)

473423

Participants

N/A

Studies

Details PubMed

GWAS 2023-08-15

Polygenic contributions to performance on the Balloon Analogue Risk Task.

Nurmi EL, Laughlin CP et al.

Mol Psychiatry

Risky decision-making is a common, heritable endophenotype seen across many psychiatric disorders. I...

Risky decision-making based on Balloon Analogue Risk Task (BART) performance

2072

Participants

N/A

Studies

Details PubMed

GWAS 2023-07-18

Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses.

Als TD, Kurki MI et al.

Nat Med

Depression is a common psychiatric disorder and a leading cause of disability worldwide. Here we con...

Depression

1349887

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-24

A genome-wide association study of antidepressant-induced mania.

Zai CC, Squassina A et al.

Prog Neuropsychopharmacol Biol Psychiatry

Antidepressant-induced mania (AIM) is a side effect of antidepressant treatment that is characterize...

Antidepressant-induced mania

814

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-13

Genetic examination of the Mood Disorder Questionnaire and its relationship with bipolar disorder.

Mundy J, Hübel C et al.

Am J Med Genet B Neuropsychiatr Genet

The Mood Disorder Questionnaire (MDQ) is a common screening tool for bipolar disorder that assesses ...

Concurrent manic symptoms in manic depressive disorder and/or anxiety disorders (sum score)

11568

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

The Genetic Architecture of the Human Corpus Callosum and its Subregions.

Bhatt RR, Gadewar SP et al.

Nat Commun

Corpus callosum total area

2025-11-04

Gene discovery and biological insights into anxiety disorders from a large-scale multi-ancestry genome-wide association study.

Friligkou E, Løkhammer S et al.

Nat Genet

Anxiety disorder

2024-09-18

Investigating the impact of poverty on mental illness in the UK Biobank using Mendelian randomization.

Marchi M, Alkema A et al.

Nat Hum Behav

Poverty (general factor)

2024-07-10

Shared genetic effect of kidney function on bipolar and major depressive disorders: a large-scale genome-wide cross-trait analysis.

Yu S, Lin Y et al.

Hum Genomics

Bipolar disorder or blood urea nitrogen levels (MTAG)

2024-06-11

Genome-wide association study of early-onset and late-onset postpartum depression: the IGEDEPP prospective study.

Tebeka S, Gloaguen E et al.

Eur Psychiatry

Early-onset postpartum depression

2024-04-01

Genetic risk for hospitalization of African American patients with severe mental illness reveals HLA loci.

Lori A, Pearce BD et al.

Front Psychiatry

Hospitalization rate in serious mental illnesses

2024-02-26

Pharmacogenomic overlap between antidepressant treatment response in major depression & antidepressant associated treatment emergent mania in bipolar disorder.

Nuñez NA, Coombes BJ et al.

Transl Psychiatry

Antidepressant-associated treatment emergent mania in BD

2024-02-13

Genetic correlation, shared loci, but no causality between bipolar disorder and inflammatory bowel disease: A genome-wide pleiotropic analysis.

Wang BR, Wang J et al.

J Affect Disord

Bipolar disorder or inflammatory bowel disease (MTAG)

2023-12-26

Polygenic contributions to performance on the Balloon Analogue Risk Task.

Nurmi EL, Laughlin CP et al.

Mol Psychiatry

Risky decision-making based on Balloon Analogue Risk Task (BART) performance

2023-08-15

Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses.

Als TD, Kurki MI et al.

Nat Med

Depression

2023-07-18

A genome-wide association study of antidepressant-induced mania.

Zai CC, Squassina A et al.

Prog Neuropsychopharmacol Biol Psychiatry

Antidepressant-induced mania

2023-05-24

Genetic examination of the Mood Disorder Questionnaire and its relationship with bipolar disorder.

Mundy J, Hübel C et al.

Am J Med Genet B Neuropsychiatr Genet

Concurrent manic symptoms in manic depressive disorder and/or anxiety disorders (sum score)

2023-05-13