Active: Bipolar disorder and schizophrenia Clear all

GWAS 2021-03-01

Kleine-Levin syndrome is associated with birth difficulties and genetic variants in the <i>TRANK1</i> gene loci.

Ambati A, Hillary R et al.

Proc Natl Acad Sci U S A

Kleine-Levin syndrome (KLS) is a rare disorder characterized by severe episodic hypersomnia, with co...

Kleine-Levin syndrome

Replicated

18139

Participants

N/A

Studies

Details PubMed

GWAS 2019-01-09

Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression.

Amare AT, Vaez A et al.

Mol Psychiatry

Although a genetic basis of depression has been well established in twin studies, identification of ...

Broad depression or major depressive disorder (self-reported)

Replicated

699951

Participants

N/A

Studies

Details PubMed

GWAS 2018-09-04

Genetics of self-reported risk-taking behaviour, trans-ethnic consistency and relevance to brain gene expression.

Strawbridge RJ, Ward J et al.

Transl Psychiatry

Risk-taking behaviour is an important component of several psychiatric disorders, including attentio...

Self-reported risk-taking behaviour

Replicated

400687

Participants

N/A

Studies

Details PubMed

GWAS 2018-05-03

Genome-wide association study for risk taking propensity indicates shared pathways with body mass index.

Clifton EAD, Perry JRB et al.

Commun Biol

Risk-taking propensity is a trait of significant public health relevance but few specific genetic fa...

Self-reported risk-taking behaviour

436236

Participants

N/A

Studies

Details PubMed

GWAS 2014-06-25

Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: a genome-wide association and polygenic scoring study.

Mullins N, Perroud N et al.

Am J Med Genet B Neuropsychiatr Genet

Epidemiological studies have recognized a genetic diathesis for suicidal behavior, which is independ...

Suicidal ideation in depression or bipolar disorder

747

Participants

N/A

Studies

Details PubMed

GWAS 2013-11-26

Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia.

Ruderfer DM, Fanous AH et al.

Mol Psychiatry

Bipolar disorder and schizophrenia are two often severe disorders with high heritabilities. Recent s...

Schizophrenia or bipolar disorder

39202

Participants

N/A

Studies

Details PubMed

GWAS 2013-09-13

Genetic predictors of risk and resilience in psychiatric disorders: a cross-disorder genome-wide association study of functional impairment in major depressive disorder, bipolar disorder, and schizophrenia.

McGrath LM, Cornelis MC et al.

Am J Med Genet B Neuropsychiatr Genet

Functional impairment is one of the most enduring, intractable consequences of psychiatric disorders...

Functional impairment in major depressive disorder, bipolar disorder and schizophrenia

2246

Participants

N/A

Studies

Details PubMed

GWAS 2010-11-04

Case-case genome-wide association analysis shows markers differentially associated with schizophrenia and bipolar disorder and implicates calcium channel genes.

Curtis D, Vine AE et al.

Psychiatr Genet

Objective: There are theoretical reasons why comparing marker allele frequencies between cases of di...

Bipolar disorder and schizophrenia

1534

Participants

N/A

Studies

Details PubMed

GWAS 2010-10-01

A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.

Wang KS, Liu XF et al.

Schizophr Res

Schizophrenia and bipolar disorder both have strong inherited components. Recent studies have indica...

Bipolar disorder and schizophrenia

4234

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Kleine-Levin syndrome is associated with birth difficulties and genetic variants in the <i>TRANK1</i> gene loci.

Ambati A, Hillary R et al.

Proc Natl Acad Sci U S A

Kleine-Levin syndrome

2021-03-01

Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression.

Amare AT, Vaez A et al.

Mol Psychiatry

Broad depression or major depressive disorder (self-reported)

2019-01-09

Genetics of self-reported risk-taking behaviour, trans-ethnic consistency and relevance to brain gene expression.

Strawbridge RJ, Ward J et al.

Transl Psychiatry

Self-reported risk-taking behaviour

2018-09-04

Genome-wide association study for risk taking propensity indicates shared pathways with body mass index.

Clifton EAD, Perry JRB et al.

Commun Biol

Self-reported risk-taking behaviour

2018-05-03

Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: a genome-wide association and polygenic scoring study.

Mullins N, Perroud N et al.

Am J Med Genet B Neuropsychiatr Genet

Suicidal ideation in depression or bipolar disorder

2014-06-25

Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia.

Ruderfer DM, Fanous AH et al.

Mol Psychiatry

Schizophrenia or bipolar disorder

2013-11-26

Genetic predictors of risk and resilience in psychiatric disorders: a cross-disorder genome-wide association study of functional impairment in major depressive disorder, bipolar disorder, and schizophrenia.

McGrath LM, Cornelis MC et al.

Am J Med Genet B Neuropsychiatr Genet

Functional impairment in major depressive disorder, bipolar disorder and schizophrenia

2013-09-13

Case-case genome-wide association analysis shows markers differentially associated with schizophrenia and bipolar disorder and implicates calcium channel genes.

Curtis D, Vine AE et al.

Psychiatr Genet

Bipolar disorder and schizophrenia

2010-11-04

A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder.

Wang KS, Liu XF et al.

Schizophr Res

Bipolar disorder and schizophrenia

2010-10-01