Active: Body mass index Clear all

GWAS 2025-11-09

Association of Multiple-trait Polygenic Risk Score with Obesity and Cardiometabolic Diseases in Korean Population.

Jo J, Ha N et al.

Genomics Proteomics Bioinformatics

We conducted a comprehensive genetic investigation of obesity in a cohort of 93,673 Korean individua...

Body mass index

Replicated

484808

Participants

N/A

Studies

Details PubMed

GWAS 2025-10-08

Characterization of prevalent genetic variants in the Estonian Biobank body-mass index GWAS.

Abner E, Batool K et al.

Nat Commun

Population-specific genome-wide association studies can reveal high-impact genomic variants that inf...

Body mass index (rank-based inverse normal transformation)

204747

Participants

N/A

Studies

Details PubMed

GWAS 2025-09-26

Genetic impact of central adiposity on systolic blood pressure in females: interaction and mediation by TG/HDL-C, HbA1c, and uric acid across BMI categories.

Gumilang RA, Bai CH

Int J Obes (Lond)

Genetic predisposition to central adiposity is associated with metabolic dysfunction and obesity-rel...

Waist circumference

49188

Participants

N/A

Studies

Details PubMed

GWAS 2025-07-01

Investigating the shared genetic architecture between adiposity measures and obesity-related cancers.

Wang S, Liu H et al.

Brief Bioinform

Fat distribution patterns are increasingly linked to obesity-related cancers; however, their shared ...

Leg fat ratio or ovarian cancer (pleiotropy)

127582

Participants

N/A

Studies

Details PubMed

GWAS 2025-06-26

Genetic associations between Serotonin Receptor 1F (<i>HTR1F</i>) regulatory variation and sleep apnea in non-obese individuals: Insights from GWAS and eQTL analyses.

Strausz S, Broberg M et al.

Eur Respir J

Sleep apnoea is a common sleep disorder affecting at least 10% of the population. It is caused by la...

Sleep apnea with BMI < 30

463876

Participants

N/A

Studies

Details PubMed

GWAS 2025-06-16

Differential Genetic Architecture of Insulin Resistance (HOMA-IR) Based on Obesity Status: Evidence from a Large-Scale GWAS of Koreans.

Choi JE, Kwon YJ et al.

Curr Issues Mol Biol

Insulin resistance (IR) is a key mechanism underlying type 2 diabetes mellitus and is closely associ...

Homeostasis model assessment of insulin resistance in normal weight

2635

Participants

N/A

Studies

Details PubMed

GWAS 2025-06-05

Contribution of genetics to hematopoietic stem cell mobilization: a genome-wide association study of 564 healthy donors mobilized with granulocyte colony-stimulating factor.

Stenzinger M, Beck S et al.

Haematologica

Hematopoietic stem and progenitor cells (HSPC) from mobilized blood are the preferred graft source f...

CD34+ cell frequency in peripheral blood following G-CSF mobilization

564

Participants

N/A

Studies

Details PubMed

GWAS 2025-05-05

Genome-Wide Association Study of Quantitative Kidney Function in 52,531 Individuals with Diabetes Identifies Five Diabetes-Specific Loci.

Cole JB, Dahlström EH et al.

J Am Soc Nephrol

Abstract Key Points: Comprehensive genome-wide association study of eGFR in diabetes, accounting for...

eGFR in diabetes mellitus (loose) kidney disease cases (minimal adjustment)

5064

Participants

N/A

Studies

Details PubMed

GWAS 2025-04-11

Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele.

Zhang X, Brody JA et al.

Nat Commun

Obesity is a major public health crisis associated with high mortality rates. Previous genome-wide a...

Body mass index

Replicated

88873

Participants

N/A

Studies

Details PubMed

GWAS 2025-03-12

GWAS identifies genetic loci, lifestyle factors and circulating biomarkers that are risk factors for sarcoidosis.

Yuan S, Chen J et al.

Nat Commun

Sarcoidosis is a complex inflammatory disease with a strong genetic component. Here, we perform a ge...

Sarcoidosis

1536622

Participants

N/A

Studies

Details PubMed

GWAS 2025-02-19

Plasma proteome variation and its genetic determinants in children and adolescents.

Niu L, Stinson SE et al.

Nat Genet

Our current understanding of the determinants of plasma proteome variation during pediatric developm...

LAD1 protein levels

1909

Participants

N/A

Studies

Details PubMed

GWAS 2025-01-29

Trans-ancestry genome wide association study of childhood body mass index identifies novel loci and age-specific effects.

Downie CG, Shrestha P et al.

HGG Adv

Over the past 30 years, obesity prevalence has markedly increased globally, including among children...

Body mass index z-score

84840

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Association of Multiple-trait Polygenic Risk Score with Obesity and Cardiometabolic Diseases in Korean Population.

Jo J, Ha N et al.

Genomics Proteomics Bioinformatics

Body mass index

2025-11-09

Characterization of prevalent genetic variants in the Estonian Biobank body-mass index GWAS.

Abner E, Batool K et al.

Nat Commun

Body mass index (rank-based inverse normal transformation)

2025-10-08

Genetic impact of central adiposity on systolic blood pressure in females: interaction and mediation by TG/HDL-C, HbA1c, and uric acid across BMI categories.

Gumilang RA, Bai CH

Int J Obes (Lond)

Waist circumference

2025-09-26

Investigating the shared genetic architecture between adiposity measures and obesity-related cancers.

Wang S, Liu H et al.

Brief Bioinform

Leg fat ratio or ovarian cancer (pleiotropy)

2025-07-01

Genetic associations between Serotonin Receptor 1F (<i>HTR1F</i>) regulatory variation and sleep apnea in non-obese individuals: Insights from GWAS and eQTL analyses.

Strausz S, Broberg M et al.

Eur Respir J

Sleep apnea with BMI < 30

2025-06-26

Differential Genetic Architecture of Insulin Resistance (HOMA-IR) Based on Obesity Status: Evidence from a Large-Scale GWAS of Koreans.

Choi JE, Kwon YJ et al.

Curr Issues Mol Biol

Homeostasis model assessment of insulin resistance in normal weight

2025-06-16

Contribution of genetics to hematopoietic stem cell mobilization: a genome-wide association study of 564 healthy donors mobilized with granulocyte colony-stimulating factor.

Stenzinger M, Beck S et al.

Haematologica

CD34+ cell frequency in peripheral blood following G-CSF mobilization

2025-06-05

Genome-Wide Association Study of Quantitative Kidney Function in 52,531 Individuals with Diabetes Identifies Five Diabetes-Specific Loci.

Cole JB, Dahlström EH et al.

J Am Soc Nephrol

eGFR in diabetes mellitus (loose) kidney disease cases (minimal adjustment)

2025-05-05

Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele.

Zhang X, Brody JA et al.

Nat Commun

Body mass index

2025-04-11

GWAS identifies genetic loci, lifestyle factors and circulating biomarkers that are risk factors for sarcoidosis.

Yuan S, Chen J et al.

Nat Commun

Sarcoidosis

2025-03-12

Plasma proteome variation and its genetic determinants in children and adolescents.

Niu L, Stinson SE et al.

Nat Genet

LAD1 protein levels

2025-02-19

Trans-ancestry genome wide association study of childhood body mass index identifies novel loci and age-specific effects.

Downie CG, Shrestha P et al.

HGG Adv

Body mass index z-score

2025-01-29