Genetic impact of central adiposity on systolic blood pressure in females: interaction and mediation by TG/HDL-C, HbA1c, and uric acid across BMI categories.
Gumilang RA, Bai CH
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Abstract
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Genetic predisposition to central adiposity is associated with metabolic dysfunction and obesity-related hypertension. This study investigated the association between genetic predisposition of general and central adiposity and systolic blood pressure (SBP) across body mass index (BMI) categories. Additionally, we explored whether, among females, the metabolic factors, triglyceride-to-HDL cholesterol (TG/HDL-C) ratio, glycated hemoglobin (HbA1c), and serum uric acid (SUA), modulate these relationships.
49,188 Taiwanese ancestry females
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