Active: Carotid intima media thickness Clear all

GWAS 2025-05-13

Metabolome-wide association identifies ferredoxin-1 (FDX1) as a determinant of cholesterol metabolism and cardiovascular risk in Asian populations.

Sadhu N, Dalan R et al.

Nat Cardiovasc Res

The burden of cardiovascular disease is rising in the Asia-Pacific region, in contrast to falling ca...

Tetradecadienoate (14:2) levels

1876

Participants

N/A

Studies

Details PubMed

GWAS 2021-12-02

Twenty-Five Novel Loci for Carotid Intima-Media Thickness: A Genome-Wide Association Study in >45 000 Individuals and Meta-Analysis of >100 000 Individuals.

Yeung MW, Wang S et al.

Arterioscler Thromb Vasc Biol

Objective: Carotid artery intima-media thickness (cIMT) is a widely accepted marker of subclinical a...

Carotid intima media thickness (minimum)

45185

Participants

N/A

Studies

Details PubMed

GWAS 2020-02-07

Novel and Known Gene-Smoking Interactions With cIMT Identified as Potential Drivers for Atherosclerosis Risk in West-African Populations of the AWI-Gen Study.

Boua PR, Brandenburg JT et al.

Front Genet

Introduction: Atherosclerosis is a key contributor to the burden of cardiovascular diseases (CVDs) a...

Carotid intima media thickness x smoking interaction

1776

Participants

N/A

Studies

Details PubMed

GWAS 2020-01-14

Analysis of the genetic variants associated with circulating levels of sgp130. Results from the IMPROVE study.

Bonomi A, Veglia F et al.

Genes Immun

The genes regulating circulating levels of soluble gp130 (sgp130), the antagonist of the inflammator...

Soluble gp130 levels

3439

Participants

N/A

Studies

Details PubMed

GWAS 2019-12-05

Carotid Intima-Media Thickness: Novel Loci, Sex-Specific Effects, and Genetic Correlations With Obesity and Glucometabolic Traits in UKB.

Strawbridge RJ, Ward J et al.

Arterioscler Thromb Vasc Biol

Objective: Atherosclerosis is the underlying cause of most cardiovascular disease, but mechanisms un...

Carotid intima media thickness (mean)

22179

Participants

N/A

Studies

Details PubMed

GWAS 2018-12-03

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.

Franceschini N, Giambartolomei C et al.

Nat Commun

Carotid artery intima media thickness (cIMT) and carotid plaque are measures of subclinical atherosc...

Carotid intima media thickness

71128

Participants

N/A

Studies

Details PubMed

GWAS 2018-09-24

A genome-wide association study identifies a 3'UTR genetic variant of RARB associated with carotid intima-media thickness in rheumatoid arthritis.

López-Mejías R, Carmona FD et al.

Arthritis Rheumatol

Objective: To investigate the genetic background influencing the development of cardiovascular (CV) ...

Carotid intima media thickness in rheumatoid arthritis

1355

Participants

N/A

Studies

Details PubMed

GWAS 2015-09-05

Genome-wide association study on progression of carotid artery intima media thickness over 10 years in a Chinese cohort.

Xie G, Myint PK et al.

Atherosclerosis

Carotid artery intima media thickness (IMT) in human is a marker of subclinical atherosclerosis with...

Carotid intima media thickness

810

Participants

N/A

Studies

Details PubMed

GWAS 2012-02-16

Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.

Demirkan A, van Duijn CM et al.

PLoS Genet

Phospho- and sphingolipids are crucial cellular and intracellular compounds. These lipids are requir...

Phospholipid levels (plasma)

4034

Participants

N/A

Studies

Details PubMed

GWAS 2011-09-11

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque.

Bis JC, Kavousi M et al.

Nat Genet

Carotid intima media thickness (cIMT) and plaque determined by ultrasonography are established measu...

Carotid intima media thickness

Replicated

42451

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Metabolome-wide association identifies ferredoxin-1 (FDX1) as a determinant of cholesterol metabolism and cardiovascular risk in Asian populations.

Sadhu N, Dalan R et al.

Nat Cardiovasc Res

Tetradecadienoate (14:2) levels

2025-05-13

Twenty-Five Novel Loci for Carotid Intima-Media Thickness: A Genome-Wide Association Study in >45 000 Individuals and Meta-Analysis of >100 000 Individuals.

Yeung MW, Wang S et al.

Arterioscler Thromb Vasc Biol

Carotid intima media thickness (minimum)

2021-12-02

Novel and Known Gene-Smoking Interactions With cIMT Identified as Potential Drivers for Atherosclerosis Risk in West-African Populations of the AWI-Gen Study.

Boua PR, Brandenburg JT et al.

Front Genet

Carotid intima media thickness x smoking interaction

2020-02-07

Analysis of the genetic variants associated with circulating levels of sgp130. Results from the IMPROVE study.

Bonomi A, Veglia F et al.

Genes Immun

Soluble gp130 levels

2020-01-14

Carotid Intima-Media Thickness: Novel Loci, Sex-Specific Effects, and Genetic Correlations With Obesity and Glucometabolic Traits in UKB.

Strawbridge RJ, Ward J et al.

Arterioscler Thromb Vasc Biol

Carotid intima media thickness (mean)

2019-12-05

GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.

Franceschini N, Giambartolomei C et al.

Nat Commun

Carotid intima media thickness

2018-12-03

A genome-wide association study identifies a 3'UTR genetic variant of RARB associated with carotid intima-media thickness in rheumatoid arthritis.

López-Mejías R, Carmona FD et al.

Arthritis Rheumatol

Carotid intima media thickness in rheumatoid arthritis

2018-09-24

Genome-wide association study on progression of carotid artery intima media thickness over 10 years in a Chinese cohort.

Xie G, Myint PK et al.

Atherosclerosis

Carotid intima media thickness

2015-09-05

Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.

Demirkan A, van Duijn CM et al.

PLoS Genet

Phospholipid levels (plasma)

2012-02-16

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque.

Bis JC, Kavousi M et al.

Nat Genet

Carotid intima media thickness

2011-09-11