Active: Corneal resistance factor Clear all

GWAS 2022-04-21

Association of Novel Loci With Keratoconus Susceptibility in a Multitrait Genome-Wide Association Study of the UK Biobank Database and Canadian Longitudinal Study on Aging.

He W, Han X et al.

JAMA Ophthalmol

Importance: Keratoconus can be a debilitating corneal ectasia in which the cornea thins, bulges, and...

Corneal resistance factor (MTAG)

123734

Participants

N/A

Studies

Details PubMed

GWAS 2020-12-11

Fine-mapping and cell-specific enrichment at corneal resistance factor loci prioritize candidate causal regulatory variants.

Jiang X, Dellepiane N et al.

Commun Biol

Corneal resistance factor (CRF) is altered during corneal diseases progression. Genome-wide-associat...

Corneal resistance factor

Replicated

86159

Participants

N/A

Studies

Details PubMed

GWAS 2020-07-27

Genome-wide association study of corneal biomechanical properties identifies over 200 loci providing insight into the genetic aetiology of ocular diseases.

Simcoe MJ, Khawaja AP et al.

Hum Mol Genet

Corneal hysteresis and corneal resistance factor are parameters that reflect the dynamic biomechanic...

Corneal hysteresis

Replicated

115070

Participants

N/A

Studies

Details PubMed

GWAS 2019-06-27

Genetic Variants Associated With Corneal Biomechanical Properties and Potentially Conferring Susceptibility to Keratoconus in a Genome-Wide Association Study.

Khawaja AP, Rojas Lopez KE et al.

JAMA Ophthalmol

Importance: Keratoconus is an important cause of visual loss in young adults, but little is known ab...

Corneal resistance factor

Replicated

9029

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Association of Novel Loci With Keratoconus Susceptibility in a Multitrait Genome-Wide Association Study of the UK Biobank Database and Canadian Longitudinal Study on Aging.

He W, Han X et al.

JAMA Ophthalmol

Corneal resistance factor (MTAG)

2022-04-21

Fine-mapping and cell-specific enrichment at corneal resistance factor loci prioritize candidate causal regulatory variants.

Jiang X, Dellepiane N et al.

Commun Biol

Corneal resistance factor

2020-12-11

Genome-wide association study of corneal biomechanical properties identifies over 200 loci providing insight into the genetic aetiology of ocular diseases.

Simcoe MJ, Khawaja AP et al.

Hum Mol Genet

Corneal hysteresis

2020-07-27

Genetic Variants Associated With Corneal Biomechanical Properties and Potentially Conferring Susceptibility to Keratoconus in a Genome-Wide Association Study.

Khawaja AP, Rojas Lopez KE et al.

JAMA Ophthalmol

Corneal resistance factor

2019-06-27