Active: Fall Clear all

GWAS 2025-05-13

Metabolome-wide association identifies ferredoxin-1 (FDX1) as a determinant of cholesterol metabolism and cardiovascular risk in Asian populations.

Sadhu N, Dalan R et al.

Nat Cardiovasc Res

The burden of cardiovascular disease is rising in the Asia-Pacific region, in contrast to falling ca...

Tetradecadienoate (14:2) levels

1876

Participants

N/A

Studies

Details PubMed

GWAS 2024-02-19

Genetic influences on circulating retinol and its relationship to human health.

Reay WR, Kiltschewskij DJ et al.

Nat Commun

Retinol is a fat-soluble vitamin that plays an essential role in many biological processes throughou...

Circulating retinol levels

Replicated

18903

Participants

N/A

Studies

Details PubMed

GWAS 2024-01-17

Genome-wide association identifies novel ROP risk loci in a multiethnic cohort.

Li X, Owen LA et al.

Commun Biol

We conducted a genome-wide association study (GWAS) in a multiethnic cohort of 920 at-risk infants f...

Retinopathy of prematurity

920

Participants

N/A

Studies

Details PubMed

GWAS 2024-01-05

Distinct and shared genetic architectures of gestational diabetes mellitus and type 2 diabetes.

Elliott A, Walters RK et al.

Nat Genet

Gestational diabetes mellitus (GDM) is a common metabolic disorder affecting more than 16 million pr...

Gestational diabetes

Replicated

323181

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-30

Genome-Wide Association Study of Chronic Dizziness in the Elderly Identifies Loci Implicating MLLT10, BPTF, LINC01224, and ROS1.

Clifford R, Munro D et al.

J Assoc Res Otolaryngol

Purpose: Chronic age-related imbalance is a common cause of falls and subsequent death in the elderl...

Chronic dizziness

417239

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-09

The genetics of falling susceptibility and identification of causal risk factors.

Smith MC, O'Loughlin J et al.

Sci Rep

Falls represent a huge health and economic burden. Whilst many factors are associated with fall risk...

Fall

201447

Participants

N/A

Studies

Details PubMed

GWAS 2023-10-16

Genome wide association joint analysis reveals 99 risk loci for pain susceptibility and pleiotropic relationships with psychiatric, metabolic, and immunological traits.

Mocci E, Ward K et al.

PLoS Genet

Chronic pain is at epidemic proportions in the United States, represents a significant burden on our...

Pain (pleiotropy)

361194

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-19

Life is pain: Fibromyalgia as a nexus of multiple liability distributions.

Moscati A, Faucon AB et al.

Am J Med Genet B Neuropsychiatr Genet

Fibromyalgia is a complex disease of unclear etiology that is complicated by difficulties in diagnos...

Fibromyalgia

16024

Participants

N/A

Studies

Details PubMed

GWAS 2022-10-01

Assessment of the genetic and clinical determinants of hip fracture risk: Genome-wide association and Mendelian randomization study.

Nethander M, Coward E et al.

Cell Rep Med

Hip fracture is the clinically most important fracture, but the genetic architecture of hip fracture...

Hip fracture

735354

Participants

N/A

Studies

Details PubMed

GWAS 2021-10-07

A genome-wide meta-analysis uncovers six sequence variants conferring risk of vertigo.

Skuladottir AT, Bjornsdottir G et al.

Commun Biol

Vertigo is the leading symptom of vestibular disorders and a major risk factor for falls. In a genom...

Vertigo

942613

Participants

N/A

Studies

Details PubMed

GWAS 2021-04-01

Genome-wide association and transcriptome analysis suggests total serum ghrelin to be linked with GFRAL.

Wittekind DA, Scholz M et al.

Eur J Endocrinol

Objective: Ghrelin is an orexigenic peptide hormone involved in the regulation of energy homeostasis...

ghrelin levels

1501

Participants

N/A

Studies

Details PubMed

GWAS 2020-10-23

MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk.

Surakka I, Fritsche LG et al.

Nat Commun

A major challenge in genetic association studies is that most associated variants fall in the non-co...

Ultradistal forearm bone mineral density

21907

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Metabolome-wide association identifies ferredoxin-1 (FDX1) as a determinant of cholesterol metabolism and cardiovascular risk in Asian populations.

Sadhu N, Dalan R et al.

Nat Cardiovasc Res

Tetradecadienoate (14:2) levels

2025-05-13

Genetic influences on circulating retinol and its relationship to human health.

Reay WR, Kiltschewskij DJ et al.

Nat Commun

Circulating retinol levels

2024-02-19

Genome-wide association identifies novel ROP risk loci in a multiethnic cohort.

Li X, Owen LA et al.

Commun Biol

Retinopathy of prematurity

2024-01-17

Distinct and shared genetic architectures of gestational diabetes mellitus and type 2 diabetes.

Elliott A, Walters RK et al.

Nat Genet

Gestational diabetes

2024-01-05

Genome-Wide Association Study of Chronic Dizziness in the Elderly Identifies Loci Implicating MLLT10, BPTF, LINC01224, and ROS1.

Clifford R, Munro D et al.

J Assoc Res Otolaryngol

Chronic dizziness

2023-11-30

The genetics of falling susceptibility and identification of causal risk factors.

Smith MC, O'Loughlin J et al.

Sci Rep

Fall

2023-11-09

Genome wide association joint analysis reveals 99 risk loci for pain susceptibility and pleiotropic relationships with psychiatric, metabolic, and immunological traits.

Mocci E, Ward K et al.

PLoS Genet

Pain (pleiotropy)

2023-10-16

Life is pain: Fibromyalgia as a nexus of multiple liability distributions.

Moscati A, Faucon AB et al.

Am J Med Genet B Neuropsychiatr Genet

Fibromyalgia

2023-06-19

Assessment of the genetic and clinical determinants of hip fracture risk: Genome-wide association and Mendelian randomization study.

Nethander M, Coward E et al.

Cell Rep Med

Hip fracture

2022-10-01

A genome-wide meta-analysis uncovers six sequence variants conferring risk of vertigo.

Skuladottir AT, Bjornsdottir G et al.

Commun Biol

Vertigo

2021-10-07

Genome-wide association and transcriptome analysis suggests total serum ghrelin to be linked with GFRAL.

Wittekind DA, Scholz M et al.

Eur J Endocrinol

ghrelin levels

2021-04-01

MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk.

Surakka I, Fritsche LG et al.

Nat Commun

Ultradistal forearm bone mineral density

2020-10-23