Active: Fasting glucose Clear all

GWAS 2025-03-01

Genome-wide association study identifying novel risk variants associated with glycaemic traits in the continental African AWI-Gen cohort.

Chebii VJ, Wade AN et al.

Diabetologia

Aims/hypothesis: Glycaemic traits such as high fasting glucose levels and insulin resistance are pos...

Fasting glucose adjusted for BMI

9989

Participants

N/A

Studies

Details PubMed

GWAS 2024-10-16

Genetic architecture of routinely acquired blood tests in a British South Asian cohort.

Jacobs BM, Stow D et al.

Nat Commun

Understanding the genetic basis of routinely-acquired blood tests can provide insights into several ...

Albumin levels

38000

Participants

N/A

Studies

Details PubMed

GWAS 2023-10-12

ADRA2A and IRX1 are putative risk genes for Raynaud's phenomenon.

Hartmann S, Yasmeen S et al.

Nat Commun

Raynaud's phenomenon (RP) is a common vasospastic disorder that causes severe pain and ulcers, but d...

Raynauds phenomenon disease

Replicated

484973

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-20

Cross-trait analyses identify shared genetics between migraine, headache, and glycemic traits, and a causal relationship with fasting proinsulin.

Islam MR, Nyholt DR

Hum Genet

The co-occurrence of migraine and glycemic traits has long been reported in observational epidemiolo...

Migraine or 2-hr glucose levels

937810

Participants

N/A

Studies

Details PubMed

GWAS 2022-11-03

Phenome-wide analysis of Taiwan Biobank reveals novel glycemia-related loci and genetic risks for diabetes.

Lee CJ, Chen TH et al.

Commun Biol

To explore the complex genetic architecture of common diseases and traits, we conducted comprehensiv...

Kidney stones

64429

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-28

Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program.

DiCorpo D, Gaynor SM et al.

Commun Biol

The genetic determinants of fasting glucose (FG) and fasting insulin (FI) have been studied mostly t...

Fasting glucose

26807

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-15

Genetic Contributors of Efficacy and Adverse Metabolic Effects of Chlorthalidone in African Americans from the Genetics of Hypertension Associated Treatments (GenHAT) Study.

Armstrong ND, Srinivasasainagendra V et al.

Genes (Basel)

Hypertension is a leading risk factor for cardiovascular disease mortality. African Americans (AAs) ...

Diastolic blood pressure response to chlorthalidone in hypertension

Replicated

4552

Participants

N/A

Studies

Details PubMed

GWAS 2021-12-24

Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study.

Downie CG, Dimos SF et al.

Diabetologia

Aims/hypothesis: Type 2 diabetes is a growing global public health challenge. Investigating quantita...

Fasting insulin adjusted for BMI

48395

Participants

N/A

Studies

Details PubMed

GWAS 2021-05-31

The trans-ancestral genomic architecture of glycemic traits.

Chen J, Spracklen CN et al.

Nat Genet

Glycemic traits are used to diagnose and monitor type 2 diabetes and cardiometabolic health. To date...

Two-hour glucose

1431

Participants

N/A

Studies

Details PubMed

GWAS 2021-04-12

Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on fasting glucose.

Chung RH, Chiu YF et al.

Diabetologia

Aims/hypothesis: An elevated fasting glucose level in non-diabetic individuals is a key predictor of...

Fasting blood glucose

Replicated

20111

Participants

N/A

Studies

Details PubMed

GWAS 2021-02-07

Circulating Adiponectin and Its Association with Metabolic Traits and Type 2 Diabetes: Gene-Diet Interactions Focusing on Selected Gene Variants and at the Genome-Wide Level in High-Cardiovascular Risk Mediterranean Subjects.

Coltell O, Ortega-Azorín C et al.

Nutrients

Adiponectin is gaining renewed interest since, in addition to its possible protective role against i...

Adiponectin levels

348

Participants

N/A

Studies

Details PubMed

GWAS 2021-01-07

A cross-platform approach identifies genetic regulators of human metabolism and health.

Lotta LA, Pietzner M et al.

Nat Genet

In cross-platform analyses of 174 metabolites, we identify 499 associations (P < 4.9 × 10-10) cha...

Phosphatidylcholine diacyl C42:1 levels

16570

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-wide association study identifying novel risk variants associated with glycaemic traits in the continental African AWI-Gen cohort.

Chebii VJ, Wade AN et al.

Diabetologia

Fasting glucose adjusted for BMI

2025-03-01

Genetic architecture of routinely acquired blood tests in a British South Asian cohort.

Jacobs BM, Stow D et al.

Nat Commun

Albumin levels

2024-10-16

ADRA2A and IRX1 are putative risk genes for Raynaud's phenomenon.

Hartmann S, Yasmeen S et al.

Nat Commun

Raynauds phenomenon disease

2023-10-12

Cross-trait analyses identify shared genetics between migraine, headache, and glycemic traits, and a causal relationship with fasting proinsulin.

Islam MR, Nyholt DR

Hum Genet

Migraine or 2-hr glucose levels

2023-02-20

Phenome-wide analysis of Taiwan Biobank reveals novel glycemia-related loci and genetic risks for diabetes.

Lee CJ, Chen TH et al.

Commun Biol

Kidney stones

2022-11-03

Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program.

DiCorpo D, Gaynor SM et al.

Commun Biol

Fasting glucose

2022-07-28

Genetic Contributors of Efficacy and Adverse Metabolic Effects of Chlorthalidone in African Americans from the Genetics of Hypertension Associated Treatments (GenHAT) Study.

Armstrong ND, Srinivasasainagendra V et al.

Genes (Basel)

Diastolic blood pressure response to chlorthalidone in hypertension

2022-07-15

Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study.

Downie CG, Dimos SF et al.

Diabetologia

Fasting insulin adjusted for BMI

2021-12-24

The trans-ancestral genomic architecture of glycemic traits.

Chen J, Spracklen CN et al.

Nat Genet

Two-hour glucose

2021-05-31

Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on fasting glucose.

Chung RH, Chiu YF et al.

Diabetologia

Fasting blood glucose

2021-04-12

Circulating Adiponectin and Its Association with Metabolic Traits and Type 2 Diabetes: Gene-Diet Interactions Focusing on Selected Gene Variants and at the Genome-Wide Level in High-Cardiovascular Risk Mediterranean Subjects.

Coltell O, Ortega-Azorín C et al.

Nutrients

Adiponectin levels

2021-02-07

A cross-platform approach identifies genetic regulators of human metabolism and health.

Lotta LA, Pietzner M et al.

Nat Genet

Phosphatidylcholine diacyl C42:1 levels

2021-01-07