Active: Fasting insulin Clear all

GWAS 2025-03-01

Genome-wide association study identifying novel risk variants associated with glycaemic traits in the continental African AWI-Gen cohort.

Chebii VJ, Wade AN et al.

Diabetologia

Aims/hypothesis: Glycaemic traits such as high fasting glucose levels and insulin resistance are pos...

Fasting glucose adjusted for BMI

9989

Participants

N/A

Studies

Details PubMed

GWAS 2023-07-07

Genetic associations vary across the spectrum of fasting serum insulin: results from the European IDEFICS/I.Family children's cohort.

Mehlig K, Foraita R et al.

Diabetologia

Aims/hypothesis: There is increasing evidence for the existence of shared genetic predictors of meta...

Fasting insulin z-score (<15th percentile)

2825

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-30

A multivariate genome-wide association study of psycho-cardiometabolic multimorbidity.

Baltramonaityte V, Pingault JB et al.

PLoS Genet

Coronary artery disease (CAD), type 2 diabetes (T2D) and depression are among the leading causes of ...

Psycho-cardiometabolic multimorbidity (multivariate analysis)

562507

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-20

Cross-trait analyses identify shared genetics between migraine, headache, and glycemic traits, and a causal relationship with fasting proinsulin.

Islam MR, Nyholt DR

Hum Genet

The co-occurrence of migraine and glycemic traits has long been reported in observational epidemiolo...

Migraine or 2-hr glucose levels

937810

Participants

N/A

Studies

Details PubMed

GWAS 2023-01-19

Genome-Wide Association Study on Longitudinal Change in Fasting Plasma Glucose in Korean Population.

Jin H, Kwak SH et al.

Diabetes Metab J

Genome-wide association studies (GWAS) on type 2 diabetes mellitus (T2DM) have identified more than ...

Fasting plasma glucose

10528

Participants

N/A

Studies

Details PubMed

GWAS 2022-08-16

Genome-wide association study of fasting proinsulin, fasting insulin, 2-hour postprandial proinsulin, and 2-hour postprandial insulin in Chinese Han people.

Lin L, Quan H et al.

Endokrynol Pol

Introduction: Fasting proinsulin (FPI) and fasting insulin (FI) have been demonstrated to be associa...

Fasting proinsulin levels in prediabetes

451

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-28

Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program.

DiCorpo D, Gaynor SM et al.

Commun Biol

The genetic determinants of fasting glucose (FG) and fasting insulin (FI) have been studied mostly t...

Fasting glucose

26807

Participants

N/A

Studies

Details PubMed

GWAS 2021-12-24

Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study.

Downie CG, Dimos SF et al.

Diabetologia

Aims/hypothesis: Type 2 diabetes is a growing global public health challenge. Investigating quantita...

Fasting insulin adjusted for BMI

48395

Participants

N/A

Studies

Details PubMed

GWAS 2021-11-04

Genome-wide association analyses highlight etiological differences underlying newly defined subtypes of diabetes.

Mansour Aly D, Dwivedi OP et al.

Nat Genet

Type 2 diabetes has been reproducibly clustered into five subtypes with different disease progressio...

Severe autoimmune type 2 diabetes

3196

Participants

N/A

Studies

Details PubMed

GWAS 2021-05-31

The trans-ancestral genomic architecture of glycemic traits.

Chen J, Spracklen CN et al.

Nat Genet

Glycemic traits are used to diagnose and monitor type 2 diabetes and cardiometabolic health. To date...

Two-hour glucose

1431

Participants

N/A

Studies

Details PubMed

GWAS 2021-01-05

Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.

Lagou V, Mägi R et al.

Nat Commun

Differences between sexes contribute to variation in the levels of fasting glucose and insulin. Epid...

Fasting glucose

140595

Participants

N/A

Studies

Details PubMed

GWAS 2020-12-30

Genome-wide association study identifying novel variant for fasting insulin and allelic heterogeneity in known glycemic loci in Chilean adolescents: The Santiago Longitudinal Study.

Buchanan VL, Wang Y et al.

Pediatr Obes

The genetic underpinnings of glycemic traits have been understudied in adolescent and Hispanic/Latin...

Fasting insulin

Replicated

44823

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-wide association study identifying novel risk variants associated with glycaemic traits in the continental African AWI-Gen cohort.

Chebii VJ, Wade AN et al.

Diabetologia

Fasting glucose adjusted for BMI

2025-03-01

Genetic associations vary across the spectrum of fasting serum insulin: results from the European IDEFICS/I.Family children's cohort.

Mehlig K, Foraita R et al.

Diabetologia

Fasting insulin z-score (<15th percentile)

2023-07-07

A multivariate genome-wide association study of psycho-cardiometabolic multimorbidity.

Baltramonaityte V, Pingault JB et al.

PLoS Genet

Psycho-cardiometabolic multimorbidity (multivariate analysis)

2023-06-30

Cross-trait analyses identify shared genetics between migraine, headache, and glycemic traits, and a causal relationship with fasting proinsulin.

Islam MR, Nyholt DR

Hum Genet

Migraine or 2-hr glucose levels

2023-02-20

Genome-Wide Association Study on Longitudinal Change in Fasting Plasma Glucose in Korean Population.

Jin H, Kwak SH et al.

Diabetes Metab J

Fasting plasma glucose

2023-01-19

Genome-wide association study of fasting proinsulin, fasting insulin, 2-hour postprandial proinsulin, and 2-hour postprandial insulin in Chinese Han people.

Lin L, Quan H et al.

Endokrynol Pol

Fasting proinsulin levels in prediabetes

2022-08-16

Whole genome sequence association analysis of fasting glucose and fasting insulin levels in diverse cohorts from the NHLBI TOPMed program.

DiCorpo D, Gaynor SM et al.

Commun Biol

Fasting glucose

2022-07-28

Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study.

Downie CG, Dimos SF et al.

Diabetologia

Fasting insulin adjusted for BMI

2021-12-24

Genome-wide association analyses highlight etiological differences underlying newly defined subtypes of diabetes.

Mansour Aly D, Dwivedi OP et al.

Nat Genet

Severe autoimmune type 2 diabetes

2021-11-04

The trans-ancestral genomic architecture of glycemic traits.

Chen J, Spracklen CN et al.

Nat Genet

Two-hour glucose

2021-05-31

Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.

Lagou V, Mägi R et al.

Nat Commun

Fasting glucose

2021-01-05

Genome-wide association study identifying novel variant for fasting insulin and allelic heterogeneity in known glycemic loci in Chilean adolescents: The Santiago Longitudinal Study.

Buchanan VL, Wang Y et al.

Pediatr Obes

Fasting insulin

2020-12-30