Active: Hemoglobin Clear all

GWAS 2025-09-26

Genetic impact of central adiposity on systolic blood pressure in females: interaction and mediation by TG/HDL-C, HbA1c, and uric acid across BMI categories.

Gumilang RA, Bai CH

Int J Obes (Lond)

Genetic predisposition to central adiposity is associated with metabolic dysfunction and obesity-rel...

Waist circumference

49188

Participants

N/A

Studies

Details PubMed

GWAS 2025-05-05

Genome-Wide Association Study of Quantitative Kidney Function in 52,531 Individuals with Diabetes Identifies Five Diabetes-Specific Loci.

Cole JB, Dahlström EH et al.

J Am Soc Nephrol

Abstract Key Points: Comprehensive genome-wide association study of eGFR in diabetes, accounting for...

eGFR in diabetes mellitus (loose) kidney disease cases (minimal adjustment)

5064

Participants

N/A

Studies

Details PubMed

GWAS 2024-06-26

Genome-wide association study identifies host genetic variants influencing oral microbiota diversity and metabolic health.

Stankevic E, Kern T et al.

Sci Rep

The microbial communities of the oral cavity are important elements of oral and systemic health. Wit...

Saliva microbiota abundance (Species parainfluenzae)

610

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-28

The value of genetic data from 665,460 individuals in managing iron deficiency anaemia and suitability to donate blood.

Toivonen J, Allara E et al.

Vox Sang

Background and objectives: Although the genetic determinants of haemoglobin and ferritin have been w...

Deferral due to hypohemoglobinemia in blood donors

27903

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-16

Analysis across Taiwan Biobank, Biobank Japan, and UK Biobank identifies hundreds of novel loci for 36 quantitative traits.

Chen CY, Chen TT et al.

Cell Genom

Genome-wide association studies (GWASs) have identified tens of thousands of genetic loci associated...

Hemoglobin

92615

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-29

Classification and deep-learning-based prediction of Alzheimer disease subtypes by using genomic data.

Shigemizu D, Akiyama S et al.

Transl Psychiatry

Late-onset Alzheimer's disease (LOAD) is the most common multifactorial neurodegenerative disease am...

Late-onset Alzheimer's disease

4139

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-15

Investigating gene-diet interactions impacting the association between macronutrient intake and glycemic traits.

Westerman KE, Walker ME et al.

Diabetes

Few studies have demonstrated reproducible gene-diet interactions (GDIs) impacting metabolic disease...

HbA1c levels x carbohydrate intake interaction (2df)

29783

Participants

N/A

Studies

Details PubMed

GWAS 2023-01-27

Comparison of the loci associated with HbA1c and blood glucose levels identified by a genome-wide association study in the Japanese population.

Sakashita T, Nakamura Y et al.

Diabetol Int

Aims: Hemoglobin A1c (HbA1c) levels are widely employed to diagnose diabetes. However, estimates of ...

Glycated hemoglobin HbA1c levels

Replicated

53605

Participants

N/A

Studies

Details PubMed

GWAS 2022-09-10

Identifying interpretable gene-biomarker associations with functionally informed kernel-based tests in 190,000 exomes.

Monti R, Rautenstrauch P et al.

Nat Commun

Here we present an exome-wide rare genetic variant association study for 30 blood biomarkers in 191,...

Glycated hemoglobin (HbA1c) levels (gene-based - predicted loss of function)

182851

Participants

N/A

Studies

Details PubMed

GWAS 2022-08-11

Common and Ethnic-Specific Genetic Determinants of Hemoglobin Concentration between Taiwanese Han Chinese and European Whites: Findings from Comparative Two-Stage Genome-Wide Association Studies.

Timoteo VJ, Chiang KM et al.

J Nutr Biochem

Human iron nutrition is a result of interplays between genetic and environmental factors. However, t...

Hemoglobin concentration

Replicated

41694

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-01

Genetic Variants Relate to Fasting Plasma Glucose, 2-Hour Postprandial Glucose, Glycosylated Hemoglobin, and BMI in Prediabetes.

Lin L, Fang T et al.

Front Endocrinol (Lausanne)

Diabetes mellitus (DM) is a chronic disease that seriously threatens human health. Prediabetes is a ...

Fasting plasma glucose in prediabetes

451

Participants

N/A

Studies

Details PubMed

GWAS 2021-11-09

An Expanded Genome-Wide Association Study of Fructosamine Levels Identifies RCN3 as a Replicating Locus and Implicates FCGRT as the Effector Transcript.

Riveros-Mckay F, Roberts D et al.

Diabetes

Fructosamine is a measure of short-term glycemic control, which has been suggested as a useful compl...

Fructosamine levels

Replicated

20731

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genetic impact of central adiposity on systolic blood pressure in females: interaction and mediation by TG/HDL-C, HbA1c, and uric acid across BMI categories.

Gumilang RA, Bai CH

Int J Obes (Lond)

Waist circumference

2025-09-26

Genome-Wide Association Study of Quantitative Kidney Function in 52,531 Individuals with Diabetes Identifies Five Diabetes-Specific Loci.

Cole JB, Dahlström EH et al.

J Am Soc Nephrol

eGFR in diabetes mellitus (loose) kidney disease cases (minimal adjustment)

2025-05-05

Genome-wide association study identifies host genetic variants influencing oral microbiota diversity and metabolic health.

Stankevic E, Kern T et al.

Sci Rep

Saliva microbiota abundance (Species parainfluenzae)

2024-06-26

The value of genetic data from 665,460 individuals in managing iron deficiency anaemia and suitability to donate blood.

Toivonen J, Allara E et al.

Vox Sang

Deferral due to hypohemoglobinemia in blood donors

2023-11-28

Analysis across Taiwan Biobank, Biobank Japan, and UK Biobank identifies hundreds of novel loci for 36 quantitative traits.

Chen CY, Chen TT et al.

Cell Genom

Hemoglobin

2023-11-16

Classification and deep-learning-based prediction of Alzheimer disease subtypes by using genomic data.

Shigemizu D, Akiyama S et al.

Transl Psychiatry

Late-onset Alzheimer's disease

2023-06-29

Investigating gene-diet interactions impacting the association between macronutrient intake and glycemic traits.

Westerman KE, Walker ME et al.

Diabetes

HbA1c levels x carbohydrate intake interaction (2df)

2023-02-15

Comparison of the loci associated with HbA1c and blood glucose levels identified by a genome-wide association study in the Japanese population.

Sakashita T, Nakamura Y et al.

Diabetol Int

Glycated hemoglobin HbA1c levels

2023-01-27

Identifying interpretable gene-biomarker associations with functionally informed kernel-based tests in 190,000 exomes.

Monti R, Rautenstrauch P et al.

Nat Commun

Glycated hemoglobin (HbA1c) levels (gene-based - predicted loss of function)

2022-09-10

Common and Ethnic-Specific Genetic Determinants of Hemoglobin Concentration between Taiwanese Han Chinese and European Whites: Findings from Comparative Two-Stage Genome-Wide Association Studies.

Timoteo VJ, Chiang KM et al.

J Nutr Biochem

Hemoglobin concentration

2022-08-11

Genetic Variants Relate to Fasting Plasma Glucose, 2-Hour Postprandial Glucose, Glycosylated Hemoglobin, and BMI in Prediabetes.

Lin L, Fang T et al.

Front Endocrinol (Lausanne)

Fasting plasma glucose in prediabetes

2022-03-01

An Expanded Genome-Wide Association Study of Fructosamine Levels Identifies RCN3 as a Replicating Locus and Implicates FCGRT as the Effector Transcript.

Riveros-Mckay F, Roberts D et al.

Diabetes

Fructosamine levels

2021-11-09