Active: IgA nephropathy Clear all

GWAS 2024-09-30

Identification of susceptibility loci and relevant cell type for IgA nephropathy in Han Chinese by integrative genome-wide analysis.

Li M, Hao X et al.

Front Med

Although many susceptibility loci for IgA nephropathy (IgAN) have been identified, they only account...

IgA nephropathy

14033

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-05

Candidate Genes for IgA Nephropathy in Pediatric Patients: Exome-Wide Association Study.

Buianova AA, Proskura MV et al.

Int J Mol Sci

IgA nephropathy (IgAN) is an autoimmune disorder which is believed to be non-monogenic. We performed...

IgA nephropathy

707

Participants

N/A

Studies

Details PubMed

GWAS 2023-10-02

Genome-Wide Association Analysis of Protein-Coding Variants in IgA Nephropathy.

Li M, Wang YN et al.

J Am Soc Nephrol

Significance statement: Genome-wide association studies have identified nearly 20 IgA nephropathy su...

IgA nephropathy

Replicated

32017

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-19

Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy.

Kiryluk K, Sanchez-Rodriguez E et al.

Nat Genet

IgA nephropathy (IgAN) is a progressive form of kidney disease defined by glomerular deposition of I...

IgA nephropathy

25852

Participants

N/A

Studies

Details PubMed

GWAS 2021-06-02

Shared genetic study gives insights into the shared and distinct pathogenic immunity components of IgA nephropathy and SLE.

Zhang YM, Zhou XJ et al.

Mol Genet Genomics

An autoimmune component has been suggested to play a role in pathogenesis of IgA nephropathy (IgAN)....

IgA nephropathy

2079

Participants

N/A

Studies

Details PubMed

GWAS 2021-02-16

Interaction between G ALNT12 and C1GALT1 Associates with Galactose-Deficient IgA1 and IgA Nephropathy.

Wang YN, Zhou XJ et al.

J Am Soc Nephrol

Galactose-deficient IgA1 plays a key role in the pathogenesis of IgA nephropathy, the most common pr...

Serum galactose-deficient IgA1 levels in IgA nephropathy

Replicated

1162

Participants

N/A

Studies

Details PubMed

GWAS 2020-09-10

Genome-Wide Meta-Analysis Identifies Three Novel Susceptibility Loci and Reveals Ethnic Heterogeneity of Genetic Susceptibility for IgA Nephropathy.

Li M, Wang L et al.

J Am Soc Nephrol

Eighteen known susceptibility loci for IgAN account for only a small proportion of IgAN risk.

IgA nephropathy

Replicated

32417

Participants

N/A

Studies

Details PubMed

GWAS 2019-08-19

Genome-wide association study identifies new susceptible loci of IgA nephropathy in Koreans.

Jeong KH, Kim JS et al.

BMC Med Genomics

Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. Recent ...

IgA nephropathy

Replicated

1391

Participants

N/A

Studies

Details PubMed

GWAS 2017-02-10

GWAS for serum galactose-deficient IgA1 implicates critical genes of the O-glycosylation pathway.

Kiryluk K, Li Y et al.

PLoS Genet

Aberrant O-glycosylation of serum immunoglobulin A1 (IgA1) represents a heritable pathogenic defect ...

Serum galactose-deficient IgA1 levels

Replicated

2633

Participants

N/A

Studies

Details PubMed

GWAS 2015-06-01

Identification of new susceptibility loci for IgA nephropathy in Han Chinese.

Li M, Foo JN et al.

Nat Commun

IgA nephropathy (IgAN) is one of the most common primary glomerulonephritis. Previously identified g...

IgA nephropathy

Replicated

27993

Participants

N/A

Studies

Details PubMed

GWAS 2014-10-12

Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens.

Kiryluk K, Li Y et al.

Nat Genet

We performed a genome-wide association study (GWAS) of IgA nephropathy (IgAN), the most common form ...

IgA nephropathy

Replicated

20612

Participants

N/A

Studies

Details PubMed

GWAS 2012-08-03

Genome-wide association study identifies TNFSF13 as a susceptibility gene for IgA in a South Chinese population in smokers.

Yang C, Jie W et al.

Immunogenetics

IgA is an important factor in our immune system. There are many diseases associated with it, such as...

IgA levels

Replicated

3495

Participants

N/A

Studies

Details PubMed

Title

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Disease/Trait

Date

Actions

Identification of susceptibility loci and relevant cell type for IgA nephropathy in Han Chinese by integrative genome-wide analysis.

Li M, Hao X et al.

Front Med

IgA nephropathy

2024-09-30

Candidate Genes for IgA Nephropathy in Pediatric Patients: Exome-Wide Association Study.

Buianova AA, Proskura MV et al.

Int J Mol Sci

IgA nephropathy

2023-11-05

Genome-Wide Association Analysis of Protein-Coding Variants in IgA Nephropathy.

Li M, Wang YN et al.

J Am Soc Nephrol

IgA nephropathy

2023-10-02

Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy.

Kiryluk K, Sanchez-Rodriguez E et al.

Nat Genet

IgA nephropathy

2023-06-19

Shared genetic study gives insights into the shared and distinct pathogenic immunity components of IgA nephropathy and SLE.

Zhang YM, Zhou XJ et al.

Mol Genet Genomics

IgA nephropathy

2021-06-02

Interaction between G ALNT12 and C1GALT1 Associates with Galactose-Deficient IgA1 and IgA Nephropathy.

Wang YN, Zhou XJ et al.

J Am Soc Nephrol

Serum galactose-deficient IgA1 levels in IgA nephropathy

2021-02-16

Genome-Wide Meta-Analysis Identifies Three Novel Susceptibility Loci and Reveals Ethnic Heterogeneity of Genetic Susceptibility for IgA Nephropathy.

Li M, Wang L et al.

J Am Soc Nephrol

IgA nephropathy

2020-09-10

Genome-wide association study identifies new susceptible loci of IgA nephropathy in Koreans.

Jeong KH, Kim JS et al.

BMC Med Genomics

IgA nephropathy

2019-08-19

GWAS for serum galactose-deficient IgA1 implicates critical genes of the O-glycosylation pathway.

Kiryluk K, Li Y et al.

PLoS Genet

Serum galactose-deficient IgA1 levels

2017-02-10

Identification of new susceptibility loci for IgA nephropathy in Han Chinese.

Li M, Foo JN et al.

Nat Commun

IgA nephropathy

2015-06-01

Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens.

Kiryluk K, Li Y et al.

Nat Genet

IgA nephropathy

2014-10-12

Genome-wide association study identifies TNFSF13 as a susceptibility gene for IgA in a South Chinese population in smokers.

Yang C, Jie W et al.

Immunogenetics

IgA levels

2012-08-03

Health & Traits Publications

Identification of susceptibility loci and relevant cell type for IgA nephropathy in Han Chinese by integrative genome-wide analysis.

Candidate Genes for IgA Nephropathy in Pediatric Patients: Exome-Wide Association Study.

Genome-Wide Association Analysis of Protein-Coding Variants in IgA Nephropathy.

Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy.

Shared genetic study gives insights into the shared and distinct pathogenic immunity components of IgA nephropathy and SLE.

Interaction between <i>G</i> <i>ALNT12</i> and <i>C1GALT1</i> Associates with Galactose-Deficient IgA1 and IgA Nephropathy.

Genome-Wide Meta-Analysis Identifies Three Novel Susceptibility Loci and Reveals Ethnic Heterogeneity of Genetic Susceptibility for IgA Nephropathy.

Genome-wide association study identifies new susceptible loci of IgA nephropathy in Koreans.

GWAS for serum galactose-deficient IgA1 implicates critical genes of the O-glycosylation pathway.

Identification of new susceptibility loci for IgA nephropathy in Han Chinese.

Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens.

Genome-wide association study identifies TNFSF13 as a susceptibility gene for IgA in a South Chinese population in smokers.