Active: Intelligence Clear all

GWAS 2025-11-04

The Genetic Architecture of the Human Corpus Callosum and its Subregions.

Bhatt RR, Gadewar SP et al.

Nat Commun

The corpus callosum (CC) is the largest set of white matter fibers connecting the two hemispheres of...

Corpus callosum total area

Replicated

51450

Participants

N/A

Studies

Details PubMed

GWAS 2025-05-15

Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline.

Schoeler T, Pingault JB et al.

Nat Commun

Large-scale genomic studies focusing on the genetic contribution to human aging have mostly relied o...

Fluid intelligence score decline (difference score)

131736

Participants

N/A

Studies

Details PubMed

GWAS 2024-06-25

Artificial intelligence-enhanced electrocardiography derived body mass index as a predictor of future cardiometabolic disease.

Pastika L, Sau A et al.

NPJ Digit Med

The electrocardiogram (ECG) can capture obesity-related cardiac changes. Artificial intelligence-enh...

Delta body mass index (difference between ECG-predicted and measured)

27988

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-14

SH2B1 Tunes Hippocampal ERK Signaling to Influence Fluid Intelligence in Humans and Mice.

Du X, Yan Y et al.

Research (Wash D C)

Fluid intelligence is a cognitive domain that encompasses general reasoning, pattern recognition, an...

Fluid intelligence

337199

Participants

N/A

Studies

Details PubMed

GWAS 2023-07-04

The impact of early adversity and education on genetic and brain morphological predictors of cognitive ability.

Corley E, Fahey L et al.

Genes Brain Behav

Cognitive ability is a strong predictor of occupational achievement, quality of life and physical he...

Intelligence using verbal-numerical reasoning

89748

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-11

Genetic susceptibility to cognitive decline following craniospinal irradiation for pediatric central nervous system tumors.

Brown AL, Sok P et al.

Neuro Oncol

Survivors of pediatric central nervous system (CNS) tumors treated with craniospinal irradiation (CS...

Change in intelligence quotient in pediatric CNS tumors treated with craniospinal irradiation

Replicated

223

Participants

N/A

Studies

Details PubMed

GWAS 2022-12-31

Deep learning-derived cardiovascular age shares a genetic basis with other cardiac phenotypes.

Libiseller-Egger J, Phelan JE et al.

Sci Rep

Artificial intelligence (AI)-based approaches can now use electrocardiograms (ECGs) to provide exper...

Cardiovascular delta age (difference between ECG-predicted and chronological age)

34432

Participants

N/A

Studies

Details PubMed

GWAS 2022-11-29

Examination of a novel expression-based gene-SNP annotation strategy to identify tissue-specific contributions to heritability in multiple traits.

Mize TJ, Evans LM

Eur J Hum Genet

Complex traits show clear patterns of tissue-specific expression influenced by single nucleotide pol...

Inflammatory bowel disease

335453

Participants

N/A

Studies

Details PubMed

GWAS 2022-11-15

A General Cognitive Ability Factor for the UK Biobank.

Williams CM, Labouret G et al.

Behav Genet

UK Biobank participants do not have a high-quality measure of intelligence or polygenic scores (PGSs...

Intelligence

223731

Participants

N/A

Studies

Details PubMed

GWAS 2022-08-23

Genome-wide analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people.

Eising E, Mirza-Schreiber N et al.

Proc Natl Acad Sci U S A

The use of spoken and written language is a fundamental human capacity. Individual differences in re...

Word reading

33959

Participants

N/A

Studies

Details PubMed

GWAS 2022-06-28

Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.

Rao S, Baranova A et al.

Neuropsychobiology

Introduction: Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) com...

Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)

371591

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-02

The individual and global impact of copy-number variants on complex human traits.

Auwerx C, Lepamets M et al.

Am J Hum Genet

The impact of copy-number variations (CNVs) on complex human traits remains understudied. We called ...

Waist-hip ratio (UKB data field 49/48) (CNV mirror model)

330926

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

The Genetic Architecture of the Human Corpus Callosum and its Subregions.

Bhatt RR, Gadewar SP et al.

Nat Commun

Corpus callosum total area

2025-11-04

Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline.

Schoeler T, Pingault JB et al.

Nat Commun

Fluid intelligence score decline (difference score)

2025-05-15

Artificial intelligence-enhanced electrocardiography derived body mass index as a predictor of future cardiometabolic disease.

Pastika L, Sau A et al.

NPJ Digit Med

Delta body mass index (difference between ECG-predicted and measured)

2024-06-25

SH2B1 Tunes Hippocampal ERK Signaling to Influence Fluid Intelligence in Humans and Mice.

Du X, Yan Y et al.

Research (Wash D C)

Fluid intelligence

2023-11-14

The impact of early adversity and education on genetic and brain morphological predictors of cognitive ability.

Corley E, Fahey L et al.

Genes Brain Behav

Intelligence using verbal-numerical reasoning

2023-07-04

Genetic susceptibility to cognitive decline following craniospinal irradiation for pediatric central nervous system tumors.

Brown AL, Sok P et al.

Neuro Oncol

Change in intelligence quotient in pediatric CNS tumors treated with craniospinal irradiation

2023-04-11

Deep learning-derived cardiovascular age shares a genetic basis with other cardiac phenotypes.

Libiseller-Egger J, Phelan JE et al.

Sci Rep

Cardiovascular delta age (difference between ECG-predicted and chronological age)

2022-12-31

Examination of a novel expression-based gene-SNP annotation strategy to identify tissue-specific contributions to heritability in multiple traits.

Mize TJ, Evans LM

Eur J Hum Genet

Inflammatory bowel disease

2022-11-29

A General Cognitive Ability Factor for the UK Biobank.

Williams CM, Labouret G et al.

Behav Genet

Intelligence

2022-11-15

Genome-wide analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people.

Eising E, Mirza-Schreiber N et al.

Proc Natl Acad Sci U S A

Word reading

2022-08-23

Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence.

Rao S, Baranova A et al.

Neuropsychobiology

Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy)

2022-06-28

The individual and global impact of copy-number variants on complex human traits.

Auwerx C, Lepamets M et al.

Am J Hum Genet

Waist-hip ratio (UKB data field 49/48) (CNV mirror model)

2022-03-02