Active: Non-small cell lung cancer Clear all

GWAS 2025-09-01

Regulatory polymorphisms of MSH6, MSH2, FBXO11, and PPP1R21 genes affect survival of patients with immunotherapy-treated lung cancer.

Esposito M, Noci S et al.

J Immunother Cancer

Immune checkpoint inhibitors (ICI) improved survival of patients with non-small cell lung cancer (NS...

Overall survival in non-small lung cancer treated with immune checkpoint inhibitors

150

Participants

N/A

Studies

Details PubMed

GWAS 2025-08-09

Non-coding genetic elements of lung cancer identified using whole genome sequencing in 13,722 Chinese.

Zhou D, Wu M et al.

Nat Commun

A substantial portion of lung cancer-associated genetic elements in East Asian populations remains u...

Non-small cell lung cancer

Replicated

13722

Participants

N/A

Studies

Details PubMed

GWAS 2025-08-01

Genome-wide association study of early-stage non-small cell lung cancer prognosis: a pooled analysis in the International Lung Cancer Consortium.

Dong M, Thakral A et al.

Carcinogenesis

Lung cancer is the leading cause of cancer mortality. To investigate genetic determinants for progno...

Late-stage non-small cell lung cancer

Replicated

3916

Participants

N/A

Studies

Details PubMed

GWAS 2023-09-02

Machine Learning Study of SNPs in Noncoding Regions to Predict Non-small Cell Lung Cancer Susceptibility.

Huang Y, Bao T et al.

Clin Oncol (R Coll Radiol)

Non-small cell lung cancer (NSCLC) is the most common pathological subtype of lung cancer. Both envi...

Non-small cell lung cancer

726

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-26

A two-stage genome-wide association study identified four potential early-onset nonsmall cell lung cancer risk loci based on 26,652 participants in Chinese population.

Fan J, Hong T et al.

Mol Carcinog

Early-onset lung cancer is rare with an increasing incidence rate. Although several genetic variants...

Early onset non-small cell lung cancer

15883

Participants

N/A

Studies

Details PubMed

GWAS 2023-05-05

Validation of lung cancer polygenic risk scores in a high-risk case-control cohort.

Lebrett MB, Smith MJ et al.

Genet Med

Purpose: Screening with low-dose computed tomography reduces lung cancer (LC) mortality. Risk predic...

Non-small cell lung cancer

1202

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-07

Establishing a Prediction Model for the Efficacy of Platinum-Based Chemotherapy in NSCLC Based on a Two Cohorts GWAS Study.

Xiao Q, Mao C et al.

J Clin Med

Platinum drugs combined with other agents have been the first-line treatment for non-small cell lung...

Response to platinum-based chemotherapy in non-small-cell lung cancer

217

Participants

N/A

Studies

Details PubMed

GWAS 2022-06-06

Associations of genetic risk, BMI trajectories, and the risk of non-small cell lung cancer: a population-based cohort study.

You D, Wang D et al.

BMC Med

Body mass index (BMI) has been found to be associated with a decreased risk of non-small cell lung c...

Non-small cell lung cancer x BMI trajectory interaction

13365

Participants

N/A

Studies

Details PubMed

GWAS 2021-05-17

A multi-omics study links TNS3 and SEPT7 to long-term former smoking NSCLC survival.

Shen S, Wei Y et al.

NPJ Precis Oncol

The genetic architecture of non-small cell lung cancer (NSCLC) is relevant to smoking status. Howeve...

Lung cancer prognosis in former smokers

1299

Participants

N/A

Studies

Details PubMed

GWAS 2020-09-05

Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma.

Qin N, Li Y et al.

Front Med

Although genome-wide association studies have identified more than eighty genetic variants associate...

Lung adenocarcinoma

42936

Participants

N/A

Studies

Details PubMed

GWAS 2018-05-15

Genomic characterization of individuals presenting extreme phenotypes of high and low risk to develop tobacco-induced lung cancer.

Fusco JP, Pita G et al.

Cancer Med

Single nucleotide polymorphisms (SNPs) may modulate individual susceptibility to carcinogens. We des...

Non-small cell lung cancer in heavy smokers

Replicated

228

Participants

N/A

Studies

Details PubMed

GWAS 2017-10-20

Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population.

Li Y, Xiao X et al.

Carcinogenesis

Non-small cell lung cancer is the most common type of lung cancer. Both environmental and genetic ri...

Smoking interaction in non-small cell lung cancer (1df test)

13336

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Regulatory polymorphisms of MSH6, MSH2, FBXO11, and PPP1R21 genes affect survival of patients with immunotherapy-treated lung cancer.

Esposito M, Noci S et al.

J Immunother Cancer

Overall survival in non-small lung cancer treated with immune checkpoint inhibitors

2025-09-01

Non-coding genetic elements of lung cancer identified using whole genome sequencing in 13,722 Chinese.

Zhou D, Wu M et al.

Nat Commun

Non-small cell lung cancer

2025-08-09

Genome-wide association study of early-stage non-small cell lung cancer prognosis: a pooled analysis in the International Lung Cancer Consortium.

Dong M, Thakral A et al.

Carcinogenesis

Late-stage non-small cell lung cancer

2025-08-01

Machine Learning Study of SNPs in Noncoding Regions to Predict Non-small Cell Lung Cancer Susceptibility.

Huang Y, Bao T et al.

Clin Oncol (R Coll Radiol)

Non-small cell lung cancer

2023-09-02

A two-stage genome-wide association study identified four potential early-onset nonsmall cell lung cancer risk loci based on 26,652 participants in Chinese population.

Fan J, Hong T et al.

Mol Carcinog

Early onset non-small cell lung cancer

2023-05-26

Validation of lung cancer polygenic risk scores in a high-risk case-control cohort.

Lebrett MB, Smith MJ et al.

Genet Med

Non-small cell lung cancer

2023-05-05

Establishing a Prediction Model for the Efficacy of Platinum-Based Chemotherapy in NSCLC Based on a Two Cohorts GWAS Study.

Xiao Q, Mao C et al.

J Clin Med

Response to platinum-based chemotherapy in non-small-cell lung cancer

2023-02-07

Associations of genetic risk, BMI trajectories, and the risk of non-small cell lung cancer: a population-based cohort study.

You D, Wang D et al.

BMC Med

Non-small cell lung cancer x BMI trajectory interaction

2022-06-06

A multi-omics study links TNS3 and SEPT7 to long-term former smoking NSCLC survival.

Shen S, Wei Y et al.

NPJ Precis Oncol

Lung cancer prognosis in former smokers

2021-05-17

Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma.

Qin N, Li Y et al.

Front Med

Lung adenocarcinoma

2020-09-05

Genomic characterization of individuals presenting extreme phenotypes of high and low risk to develop tobacco-induced lung cancer.

Fusco JP, Pita G et al.

Cancer Med

Non-small cell lung cancer in heavy smokers

2018-05-15

Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population.

Li Y, Xiao X et al.

Carcinogenesis

Smoking interaction in non-small cell lung cancer (1df test)

2017-10-20