Active: Nonsyndromic cleft lip Clear all

GWAS 2024-04-18

Shared genetic risk between major orofacial cleft phenotypes in an African population.

Alade A, Peter T et al.

Genet Epidemiol

Nonsyndromic orofacial clefts (NSOFCs) represent a large proportion (70%-80%) of all OFCs. They can ...

Cleft lip with or without cleft palate or cleft palate (pleiotropy)

3178

Participants

N/A

Studies

Details PubMed

GWAS 2024-03-01

Integrative Multi-omics Analysis Identifies Genetic Variants Contributing to Non-syndromic Cleft Lip with or without Cleft Palate.

Lou S, Yang J et al.

Chin J Dent Res

Objective: To provide novel insights into the aetiology of non-syndromic cleft lip with or without c...

Nonsyndromic cleft lip with or without cleft palate

Replicated

2793

Participants

N/A

Studies

Details PubMed

GWAS 2021-12-08

Identification of Novel Genomic Variations in Susceptibility to Nonsyndromic Cleft Lip and Palate Patients.

Avasthi KK, Muthuswamy S et al.

Pediatr Rep

Nonsyndromic cleft lip with or without palate (NSCL/P) is a multifactorial and common birth malforma...

Nonsyndromic cleft lip with or without cleft palate

Participants

N/A

Studies

Details PubMed

GWAS 2021-04-09

Genome-Wide Association Study of Non-syndromic Orofacial Clefts in a Multiethnic Sample of Families and Controls Identifies Novel Regions.

Mukhopadhyay N, Feingold E et al.

Front Cell Dev Biol

Orofacial clefts (OFCs) are among the most prevalent craniofacial birth defects worldwide and create...

Nonsyndromic cleft lip with or without cleft palate

9447

Participants

N/A

Studies

Details PubMed

GWAS 2020-08-06

Genome-wide Analyses Identify a Novel Risk Locus for Nonsyndromic Cleft Palate.

He M, Zuo X et al.

J Dent Res

The 3 major subphenotypes observed in patients with nonsyndromic orofacial clefts (NSOFCs) are nonsy...

Nonsyndromic cleft palate

Replicated

11404

Participants

N/A

Studies

Details PubMed

GWAS 2019-10-14

Genetic factors define CPO and CLO subtypes of nonsyndromicorofacial cleft.

Huang L, Jia Z et al.

PLoS Genet

Nonsyndromic orofacial cleft (NSOFC) is a severe birth defect that occurs early in embryonic develop...

Nonsyndromic cleft lip

Replicated

12363

Participants

N/A

Studies

Details PubMed

GWAS 2018-09-11

Genome-wide interaction studies identify sex-specific risk alleles for nonsyndromic orofacial clefts.

Carlson JC, Nidey NL et al.

Genet Epidemiol

Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is the most common craniofacial birth d...

Nonsyndromic cleft lip with or without cleft palate x sex interaction (2df test)

3842

Participants

N/A

Studies

Details PubMed

GWAS 2017-02-24

Genome-wide analyses of non-syndromic cleft lip with palate identify 14 novel loci and genetic heterogeneity.

Yu Y, Zuo X et al.

Nat Commun

Non-syndromic cleft lip with palate (NSCLP) is the most serious sub-phenotype of non-syndromic orofa...

Nonsyndromic cleft lip with cleft palate

Replicated

11972

Participants

N/A

Studies

Details PubMed

GWAS 2017-01-13

Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only.

Ludwig KU, Böhmer AC et al.

Hum Mol Genet

Nonsyndromic cleft lip with or without cleft palate (nsCL/P) is among the most common human birth de...

Nonsyndromic cleft lip with or without cleft palate

Replicated

8309

Participants

N/A

Studies

Details PubMed

GWAS 2015-03-16

Genome-wide association study identifies a new susceptibility locus for cleft lip with or without a cleft palate.

Sun Y, Huang Y et al.

Nat Commun

Nonsyndromic cleft lip with or without a cleft palate (NSCL/P) is among the most common human congen...

Nonsyndromic cleft lip with or without cleft palate

Replicated

5643

Participants

N/A

Studies

Details PubMed

GWAS 2012-08-05

Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci.

Ludwig KU, Mangold E et al.

Nat Genet

We have conducted the first meta-analyses for nonsyndromic cleft lip with or without cleft palate (N...

Orofacial clefts

Replicated

6100

Participants

N/A

Studies

Details PubMed

GWAS 2009-12-20

Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate.

Mangold E, Ludwig KU et al.

Nat Genet

We conducted a genome-wide association study for nonsyndromic cleft lip with or without cleft palate...

Orofacial clefts

Replicated

2372

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Shared genetic risk between major orofacial cleft phenotypes in an African population.

Alade A, Peter T et al.

Genet Epidemiol

Cleft lip with or without cleft palate or cleft palate (pleiotropy)

2024-04-18

Integrative Multi-omics Analysis Identifies Genetic Variants Contributing to Non-syndromic Cleft Lip with or without Cleft Palate.

Lou S, Yang J et al.

Chin J Dent Res

Nonsyndromic cleft lip with or without cleft palate

2024-03-01

Identification of Novel Genomic Variations in Susceptibility to Nonsyndromic Cleft Lip and Palate Patients.

Avasthi KK, Muthuswamy S et al.

Pediatr Rep

Nonsyndromic cleft lip with or without cleft palate

2021-12-08

Genome-Wide Association Study of Non-syndromic Orofacial Clefts in a Multiethnic Sample of Families and Controls Identifies Novel Regions.

Mukhopadhyay N, Feingold E et al.

Front Cell Dev Biol

Nonsyndromic cleft lip with or without cleft palate

2021-04-09

Genome-wide Analyses Identify a Novel Risk Locus for Nonsyndromic Cleft Palate.

He M, Zuo X et al.

J Dent Res

Nonsyndromic cleft palate

2020-08-06

Genetic factors define CPO and CLO subtypes of nonsyndromicorofacial cleft.

Huang L, Jia Z et al.

PLoS Genet

Nonsyndromic cleft lip

2019-10-14

Genome-wide interaction studies identify sex-specific risk alleles for nonsyndromic orofacial clefts.

Carlson JC, Nidey NL et al.

Genet Epidemiol

Nonsyndromic cleft lip with or without cleft palate x sex interaction (2df test)

2018-09-11

Genome-wide analyses of non-syndromic cleft lip with palate identify 14 novel loci and genetic heterogeneity.

Yu Y, Zuo X et al.

Nat Commun

Nonsyndromic cleft lip with cleft palate

2017-02-24

Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only.

Ludwig KU, Böhmer AC et al.

Hum Mol Genet

Nonsyndromic cleft lip with or without cleft palate

2017-01-13

Genome-wide association study identifies a new susceptibility locus for cleft lip with or without a cleft palate.

Sun Y, Huang Y et al.

Nat Commun

Nonsyndromic cleft lip with or without cleft palate

2015-03-16

Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci.

Ludwig KU, Mangold E et al.

Nat Genet

Orofacial clefts

2012-08-05

Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate.

Mangold E, Ludwig KU et al.

Nat Genet

Orofacial clefts

2009-12-20