Active: Physical activity Clear all

GWAS 2024-07-04

Principled distillation of UK Biobank phenotype data reveals underlying structure in human variation.

Carey CE, Shafee R et al.

Nat Hum Behav

Data within biobanks capture broad yet detailed indices of human variation, but biobank-wide insight...

Age-related eyesight deterioration (confirmatory factor analysis Factor 27)

80058

Participants

N/A

Studies

Details PubMed

GWAS 2024-01-02

Risk factors associated with age at onset of Parkinson's disease in the UK Biobank.

Huang Y, Chen Q et al.

NPJ Parkinsons Dis

Substantial evidence shown that the age at onset (AAO) of Parkinson's disease (PD) is a major determ...

Parkinson's disease (age of onset) x smoking interaction

3124

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-17

New Insights into Polygenic Score-Lifestyle Interactions for Cardiometabolic Risk Factors from Genome-Wide Interaction Analyses.

D'Urso S, Hwang LD

Nutrients

The relationship between lifestyles and cardiometabolic outcomes varies between individuals. In 382,...

BMI x meat diet interaction

382375

Participants

N/A

Studies

Details PubMed

GWAS 2023-11-09

The genetics of falling susceptibility and identification of causal risk factors.

Smith MC, O'Loughlin J et al.

Sci Rep

Falls represent a huge health and economic burden. Whilst many factors are associated with fall risk...

Fall

201447

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-27

Participation bias in the UK Biobank distorts genetic associations and downstream analyses.

Schoeler T, Speed D et al.

Nat Hum Behav

While volunteer-based studies such as the UK Biobank have become the cornerstone of genetic epidemio...

Physical activity (standard GWA)

271843

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-16

A genome-wide association study of frailty identifies significant genetic correlation with neuropsychiatric, cardiovascular, and inflammation pathways.

Ye Y, Noche RB et al.

Geroscience

Frailty is an aging-related clinical phenotype defined as a state in which there is an increase in a...

Fried Frailty Score

Replicated

396285

Participants

N/A

Studies

Details PubMed

GWAS 2022-12-12

Genome-wide assessment reveals a significant association between ACSS3 and physical activity.

Jo J, Song Y et al.

Genes Brain Behav

Recent genetic studies have identified physical activity (PA)-susceptible loci in European ancestry ...

Physical activity

Replicated

325202

Participants

N/A

Studies

Details PubMed

GWAS 2022-09-07

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention.

Wang Z, Emmerich A et al.

Nat Genet

Although physical activity and sedentary behavior are moderately heritable, little is known about th...

Leisure screen time

526725

Participants

N/A

Studies

Details PubMed

GWAS 2022-08-02

Association of sedentary and physical activity behaviours with body composition: a genome-wide association and Mendelian randomisation study.

Ramadan FA, Bea JW et al.

BMJ Open Sport Exerc Med

Objectives: Studies suggest that body composition can be independently improved through physical act...

Moderate physical activity

360911

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-30

Genome-Wide Interaction Study of Late-Onset Asthma With Seven Environmental Factors Using a Structured Linear Mixed Model in Europeans.

Baek EJ, Jung HU et al.

Front Genet

Asthma is among the most common chronic diseases worldwide, creating a substantial healthcare burden...

Asthma x body mass index interaction

Replicated

230606

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-11

Genome-wide Association Study of Liking for Several Types of Physical Activity in the UK Biobank and Two Replication Cohorts.

Klimentidis YC, Newell M et al.

Med Sci Sports Exerc

Introduction: A lack of physical activity (PA) is one of the most pressing health issues today. Our ...

Liking for working up a sweat

Replicated

167534

Participants

N/A

Studies

Details PubMed

GWAS 2021-11-09

The genetic case for cardiorespiratory fitness as a clinical vital sign and the routine prescription of physical activity in healthcare.

Hanscombe KB, Persyn E et al.

Genome Med

Cardiorespiratory fitness (CRF) and physical activity (PA) are well-established predictors of morbid...

Cardiorespiratory fitness (vo2 max)

70783

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Principled distillation of UK Biobank phenotype data reveals underlying structure in human variation.

Carey CE, Shafee R et al.

Nat Hum Behav

Age-related eyesight deterioration (confirmatory factor analysis Factor 27)

2024-07-04

Risk factors associated with age at onset of Parkinson's disease in the UK Biobank.

Huang Y, Chen Q et al.

NPJ Parkinsons Dis

Parkinson's disease (age of onset) x smoking interaction

2024-01-02

New Insights into Polygenic Score-Lifestyle Interactions for Cardiometabolic Risk Factors from Genome-Wide Interaction Analyses.

D'Urso S, Hwang LD

Nutrients

BMI x meat diet interaction

2023-11-17

The genetics of falling susceptibility and identification of causal risk factors.

Smith MC, O'Loughlin J et al.

Sci Rep

Fall

2023-11-09

Participation bias in the UK Biobank distorts genetic associations and downstream analyses.

Schoeler T, Speed D et al.

Nat Hum Behav

Physical activity (standard GWA)

2023-04-27

A genome-wide association study of frailty identifies significant genetic correlation with neuropsychiatric, cardiovascular, and inflammation pathways.

Ye Y, Noche RB et al.

Geroscience

Fried Frailty Score

2023-03-16

Genome-wide assessment reveals a significant association between ACSS3 and physical activity.

Jo J, Song Y et al.

Genes Brain Behav

Physical activity

2022-12-12

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention.

Wang Z, Emmerich A et al.

Nat Genet

Leisure screen time

2022-09-07

Association of sedentary and physical activity behaviours with body composition: a genome-wide association and Mendelian randomisation study.

Ramadan FA, Bea JW et al.

BMJ Open Sport Exerc Med

Moderate physical activity

2022-08-02

Genome-Wide Interaction Study of Late-Onset Asthma With Seven Environmental Factors Using a Structured Linear Mixed Model in Europeans.

Baek EJ, Jung HU et al.

Front Genet

Asthma x body mass index interaction

2022-03-30

Genome-wide Association Study of Liking for Several Types of Physical Activity in the UK Biobank and Two Replication Cohorts.

Klimentidis YC, Newell M et al.

Med Sci Sports Exerc

Liking for working up a sweat

2022-03-11

The genetic case for cardiorespiratory fitness as a clinical vital sign and the routine prescription of physical activity in healthcare.

Hanscombe KB, Persyn E et al.

Genome Med

Cardiorespiratory fitness (vo2 max)

2021-11-09