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GWAS Study

The genetic case for cardiorespiratory fitness as a clinical vital sign and the routine prescription of physical activity in healthcare.

Hanscombe KB, Persyn E, Traylor M et al.

34753499 PubMed ID
GWAS Study Type
70783 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

HK
Hanscombe KB
PE
Persyn E
TM
Traylor M
GK
Glanville KP
HM
Hamer M
CJ
Coleman JRI
LC
Lewis CM
Chapter II

Abstract

Summary of the research findings

Cardiorespiratory fitness (CRF) and physical activity (PA) are well-established predictors of morbidity and all-cause mortality. However, CRF is not routinely measured and PA not routinely prescribed as part of standard healthcare. The American Heart Association (AHA) recently presented a scientific case for the inclusion of CRF as a clinical vital sign based on epidemiological and clinical observation. Here, we leverage genetic data in the UK Biobank (UKB) to strengthen the case for CRF as a vital sign and make a case for the prescription of PA.

70,783 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

70783
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.K.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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