Active: Squamous cell carcinoma Clear all

GWAS 2025-08-01

Genome-wide association study of early-stage non-small cell lung cancer prognosis: a pooled analysis in the International Lung Cancer Consortium.

Dong M, Thakral A et al.

Carcinogenesis

Lung cancer is the leading cause of cancer mortality. To investigate genetic determinants for progno...

Late-stage non-small cell lung cancer

Replicated

3916

Participants

N/A

Studies

Details PubMed

GWAS 2025-05-08

Genome-wide association study for lung cancer in 6531 African Americans reveals new susceptibility loci.

Byun J, Han Y et al.

Hum Mol Genet

Despite lung cancer affecting all races and ethnicities, disparities are observed in incidence and m...

Lung adenocarcinoma

5274

Participants

N/A

Studies

Details PubMed

GWAS 2024-12-31

Shared genetic factors and the interactions with fresh fruit intake contributes to four types squamous cell carcinomas.

Mo M, Hou C et al.

PLoS One

Studies have reported risk factors for a single-squamous cell carcinoma(Single-SCCs). However, the s...

Pan-squamous cell carcinoma

9640

Participants

N/A

Studies

Details PubMed

GWAS 2024-05-03

PTPN23[Thr] variant reduces susceptibility and tumorigenesis in esophageal squamous cell carcinoma through dephosphorylation of EGFR.

Niu S, Ma J et al.

Cancer Lett

Post-translational modifications (PTMs) have emerged as pivotal regulators of the development of can...

Esophageal squamous cell carcinoma

Replicated

33816

Participants

N/A

Studies

Details PubMed

GWAS 2024-01-05

Multi-ancestry genome-wide meta-analysis identifies novel basal cell carcinoma loci and shared genetic effects with squamous cell carcinoma.

Choquet H, Jiang C et al.

Commun Biol

Basal cell carcinoma (BCC) is one of the most common malignancies worldwide, yet its genetic determi...

Basal cell carcinoma

802297

Participants

N/A

Studies

Details PubMed

GWAS 2023-09-14

Single-nucleotide polymorphism at alcohol dehydrogenase 1B: A susceptible gene marker in oro-/hypopharyngeal cancers from genome-wide association study.

Chien HT, Tsai CL et al.

Cancer Med

Introduction: In the era of precision preventive medicine, susceptible genetic markers for oro-/hypo...

Oropharyngeal or hypopharyngeal squamous cell carcinoma

2731

Participants

N/A

Studies

Details PubMed

GWAS 2023-08-29

Genome-wide association study of esophageal squamous cell cancer identifies shared and distinct risk variants in African and Chinese populations.

Chen WC, Brandenburg JT et al.

Am J Hum Genet

Esophageal squamous cell carcinoma (ESCC) has a high disease burden in sub-Saharan Africa and has a ...

Esophageal squamous cell carcinoma

4903

Participants

N/A

Studies

Details PubMed

GWAS 2022-12-10

A multi-phenotype analysis reveals 19 susceptibility loci for basal cell carcinoma and 15 for squamous cell carcinoma.

Seviiri M, Law MH et al.

Nat Commun

Basal cell carcinoma and squamous cell carcinoma are the most common skin cancers, and have genetic ...

Basal cell carcinoma (MTAG)

Replicated

2831314

Participants

N/A

Studies

Details PubMed

GWAS 2021-12-07

Host Genetic Associations with Salivary Microbiome in Oral Cancer.

Yang SF, Lin CW et al.

J Dent Res

Despite the growing recognition of a host genetic effect on shaping gut microbiota composition, the ...

Oral microbiota abundance (Lachnoanaerobaculum) in oral squamous cell carcinoma

Replicated

211

Participants

N/A

Studies

Details PubMed

GWAS 2021-06-01

Aberrant MCM10 SUMOylation induces genomic instability mediated by a genetic variant associated with survival of esophageal squamous cell carcinoma.

Tian J, Lu Z et al.

Clin Transl Med

Esophageal squamous cell carcinoma (ESCC) is one of the common gastrointestinal malignancy with an i...

Survival time in esophageal squamous cell carcinoma

Replicated

1407

Participants

N/A

Studies

Details PubMed

GWAS 2021-03-05

Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers.

Lesseur C, Ferreiro-Iglesias A et al.

PLoS Genet

Squamous cell carcinomas (SqCC) of the aerodigestive tract have similar etiological risk factors. Al...

Aerodigestive squamous cell cancer (pleiotropy)

75848

Participants

N/A

Studies

Details PubMed

GWAS 2020-09-05

Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma.

Qin N, Li Y et al.

Front Med

Although genome-wide association studies have identified more than eighty genetic variants associate...

Lung adenocarcinoma

42936

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genome-wide association study of early-stage non-small cell lung cancer prognosis: a pooled analysis in the International Lung Cancer Consortium.

Dong M, Thakral A et al.

Carcinogenesis

Late-stage non-small cell lung cancer

2025-08-01

Genome-wide association study for lung cancer in 6531 African Americans reveals new susceptibility loci.

Byun J, Han Y et al.

Hum Mol Genet

Lung adenocarcinoma

2025-05-08

Shared genetic factors and the interactions with fresh fruit intake contributes to four types squamous cell carcinomas.

Mo M, Hou C et al.

PLoS One

Pan-squamous cell carcinoma

2024-12-31

PTPN23[Thr] variant reduces susceptibility and tumorigenesis in esophageal squamous cell carcinoma through dephosphorylation of EGFR.

Niu S, Ma J et al.

Cancer Lett

Esophageal squamous cell carcinoma

2024-05-03

Multi-ancestry genome-wide meta-analysis identifies novel basal cell carcinoma loci and shared genetic effects with squamous cell carcinoma.

Choquet H, Jiang C et al.

Commun Biol

Basal cell carcinoma

2024-01-05

Single-nucleotide polymorphism at alcohol dehydrogenase 1B: A susceptible gene marker in oro-/hypopharyngeal cancers from genome-wide association study.

Chien HT, Tsai CL et al.

Cancer Med

Oropharyngeal or hypopharyngeal squamous cell carcinoma

2023-09-14

Genome-wide association study of esophageal squamous cell cancer identifies shared and distinct risk variants in African and Chinese populations.

Chen WC, Brandenburg JT et al.

Am J Hum Genet

Esophageal squamous cell carcinoma

2023-08-29

A multi-phenotype analysis reveals 19 susceptibility loci for basal cell carcinoma and 15 for squamous cell carcinoma.

Seviiri M, Law MH et al.

Nat Commun

Basal cell carcinoma (MTAG)

2022-12-10

Host Genetic Associations with Salivary Microbiome in Oral Cancer.

Yang SF, Lin CW et al.

J Dent Res

Oral microbiota abundance (Lachnoanaerobaculum) in oral squamous cell carcinoma

2021-12-07

Aberrant MCM10 SUMOylation induces genomic instability mediated by a genetic variant associated with survival of esophageal squamous cell carcinoma.

Tian J, Lu Z et al.

Clin Transl Med

Survival time in esophageal squamous cell carcinoma

2021-06-01

Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers.

Lesseur C, Ferreiro-Iglesias A et al.

PLoS Genet

Aerodigestive squamous cell cancer (pleiotropy)

2021-03-05

Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma.

Qin N, Li Y et al.

Front Med

Lung adenocarcinoma

2020-09-05