Active: Stroke Clear all

GWAS 2025-12-01

Genetic determinants of zinc homeostasis and its role in cardiometabolic diseases.

Sadler MC, Ghobril JP et al.

PLoS Genet

Zinc is essential for many physiological processes and its deficiency is highly prevalent worldwide....

Urinary zinc levels

10103

Participants

N/A

Studies

Details PubMed

GWAS 2025-06-13

Beyond volume: Unraveling the genetics of human brain geometry.

Primus SA, Hoffstaedter F et al.

Sci Adv

Brain geometry affects brain function. A quantitative encoding of form is provided by the Laplace-Be...

Left accumbens area shape (Laplace-Beltrami spectrum)

Replicated

24823

Participants

N/A

Studies

Details PubMed

GWAS 2025-03-06

Meta-analysis of genome-wide associations and polygenic risk prediction for atrial fibrillation in more than 180,000 cases.

Roselli C, Surakka I et al.

Nat Genet

Atrial fibrillation (AF) is the most common heart rhythm abnormality and is a leading cause of heart...

Atrial fibrillation

1650345

Participants

N/A

Studies

Details PubMed

GWAS 2025-01-17

Genome-wide and phenome-wide studies provided insights into brain glymphatic system function and its clinical associations.

Ran L, Fang Y et al.

Sci Adv

We applied an MRI technique diffusion tensor imaging along the perivascular space (DTI-ALPS) for ass...

Anterior diffusion tensor imaging along the perivascular space index

31629

Participants

N/A

Studies

Details PubMed

GWAS 2024-09-13

NOTCH3 p.Arg1231Cys is markedly enriched in South Asians and associated with stroke.

Rodriguez-Flores JL, Khalid S et al.

Nat Commun

The genetic factors of stroke in South Asians are largely unexplored. Exome-wide sequencing and asso...

Intracerebral hemorrhage stroke

Replicated

28135

Participants

N/A

Studies

Details PubMed

GWAS 2024-09-02

Evidence of survival bias in the association between <i>APOE-Є4</i> and age at ischemic stroke onset.

von Berg J, McArdle PF et al.

Front Genet

Introduction: Large genome-wide association studies (GWASs) using case-control study designs have no...

Age of onset of ischemic stroke

Replicated

22396

Participants

N/A

Studies

Details PubMed

GWAS 2024-06-26

Genome-wide association study identifies host genetic variants influencing oral microbiota diversity and metabolic health.

Stankevic E, Kern T et al.

Sci Rep

The microbial communities of the oral cavity are important elements of oral and systemic health. Wit...

Saliva microbiota abundance (Species parainfluenzae)

610

Participants

N/A

Studies

Details PubMed

GWAS 2024-06-11

Whole-genome sequencing identifies variants in ANK1, LRRN1, HAS1, and other genes and regulatory regions for stroke in type 1 diabetes.

Antikainen AA, Haukka JK et al.

Sci Rep

Individuals with type 1 diabetes (T1D) carry a markedly increased risk of stroke, with distinct clin...

Stroke in type 1 diabetes

Replicated

4996

Participants

N/A

Studies

Details PubMed

GWAS 2024-05-21

Deep learning of left atrial structure and function provides link to atrial fibrillation risk.

Pirruccello JP, Di Achille P et al.

Nat Commun

Increased left atrial volume and decreased left atrial function have long been associated with atria...

Left atrial maximum volume

35049

Participants

N/A

Studies

Details PubMed

GWAS 2024-03-25

Does Thrombosis Play a Causal Role in Lacunar Stroke and Cerebral Small Vessel Disease?

Koohi F, Harshfield EL et al.

Stroke

The importance of thromboembolism in the pathogenesis of lacunar stroke (LS), resulting from cerebra...

White matter hyperintensities

37355

Participants

N/A

Studies

Details PubMed

GWAS 2024-02-20

Interplay between Polygenic Variants Related Immune Response and Lifestyle Factors Mitigate the Chances of Stroke in a Genome-Wide Association Study.

Park S

Br J Nutr

We aimed to investigate the intricate interplay between genetic predisposition and lifestyle factors...

Stroke

58701

Participants

N/A

Studies

Details PubMed

GWAS 2024-02-05

Novel functional insights into ischemic stroke biology provided by the first genome-wide association study of stroke in indigenous Africans.

Akinyemi RO, Tiwari HK et al.

Genome Med

African ancestry populations have the highest burden of stroke worldwide, yet the genetic basis of s...

Ischemic stroke

3421

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genetic determinants of zinc homeostasis and its role in cardiometabolic diseases.

Sadler MC, Ghobril JP et al.

PLoS Genet

Urinary zinc levels

2025-12-01

Beyond volume: Unraveling the genetics of human brain geometry.

Primus SA, Hoffstaedter F et al.

Sci Adv

Left accumbens area shape (Laplace-Beltrami spectrum)

2025-06-13

Meta-analysis of genome-wide associations and polygenic risk prediction for atrial fibrillation in more than 180,000 cases.

Roselli C, Surakka I et al.

Nat Genet

Atrial fibrillation

2025-03-06

Genome-wide and phenome-wide studies provided insights into brain glymphatic system function and its clinical associations.

Ran L, Fang Y et al.

Sci Adv

Anterior diffusion tensor imaging along the perivascular space index

2025-01-17

NOTCH3 p.Arg1231Cys is markedly enriched in South Asians and associated with stroke.

Rodriguez-Flores JL, Khalid S et al.

Nat Commun

Intracerebral hemorrhage stroke

2024-09-13

Evidence of survival bias in the association between <i>APOE-Є4</i> and age at ischemic stroke onset.

von Berg J, McArdle PF et al.

Front Genet

Age of onset of ischemic stroke

2024-09-02

Genome-wide association study identifies host genetic variants influencing oral microbiota diversity and metabolic health.

Stankevic E, Kern T et al.

Sci Rep

Saliva microbiota abundance (Species parainfluenzae)

2024-06-26

Whole-genome sequencing identifies variants in ANK1, LRRN1, HAS1, and other genes and regulatory regions for stroke in type 1 diabetes.

Antikainen AA, Haukka JK et al.

Sci Rep

Stroke in type 1 diabetes

2024-06-11

Deep learning of left atrial structure and function provides link to atrial fibrillation risk.

Pirruccello JP, Di Achille P et al.

Nat Commun

Left atrial maximum volume

2024-05-21

Does Thrombosis Play a Causal Role in Lacunar Stroke and Cerebral Small Vessel Disease?

Koohi F, Harshfield EL et al.

Stroke

White matter hyperintensities

2024-03-25

Interplay between Polygenic Variants Related Immune Response and Lifestyle Factors Mitigate the Chances of Stroke in a Genome-Wide Association Study.

Park S

Br J Nutr

Stroke

2024-02-20

Novel functional insights into ischemic stroke biology provided by the first genome-wide association study of stroke in indigenous Africans.

Akinyemi RO, Tiwari HK et al.

Genome Med

Ischemic stroke

2024-02-05