Active: Total cholesterol levels Clear all

GWAS 2024-12-19

Population-specific reference panel improves imputation quality for genome-wide association studies conducted on the Japanese population.

Flanagan J, Liu X et al.

Commun Biol

To improve imputation quality for genome-wide association studies (GWAS) conducted on the Japanese p...

Total cholesterol levels (1KG-JEWEL7K)

181927

Participants

N/A

Studies

Details PubMed

GWAS 2023-09-05

Multi-trait discovery and fine-mapping of lipid loci in 125,000 individuals of African ancestry.

Kamiza AB, Touré SM et al.

Nat Commun

Most genome-wide association studies (GWAS) for lipid traits focus on the separate analysis of lipid...

Total cholesterol levels

125000

Participants

N/A

Studies

Details PubMed

GWAS 2023-01-06

Exploring the Genetic Association between Obesity and Serum Lipid Levels Using Bivariate Methods.

Ke J, Gao W et al.

Twin Res Hum Genet

It is crucial to understand the genetic mechanisms and biological pathways underlying the relationsh...

Body mass index and total cholesterol levels

Replicated

746

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-06

Dyslipidaemia-Genotype Interactions with Nutrient Intake and Cerebro-Cardiovascular Disease.

Lee SB, Choi JE et al.

Biomedicines

A comprehensive understanding of gene-diet interactions is necessary to establish proper dietary gui...

Total cholesterol levels

58701

Participants

N/A

Studies

Details PubMed

GWAS 2021-01-18

Tractor uses local ancestry to enable the inclusion of admixed individuals in GWAS and to boost power.

Atkinson EG, Maihofer AX et al.

Nat Genet

Admixed populations are routinely excluded from genomic studies due to concerns over population stru...

Total cholesterol levels (joint analysis model with African background)

4309

Participants

N/A

Studies

Details PubMed

GWAS 2018-11-15

Heritability and Genome-Wide Association Study of Plasma Cholesterol in Chinese Adult Twins.

Liu H, Wang W et al.

Front Endocrinol (Lausanne)

Dyslipidemia represents a strong and independent risk factor for cardiovascular disease. Plasma chol...

Total cholesterol levels

278

Participants

N/A

Studies

Details PubMed

GWAS 2018-02-05

Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.

Kanai M, Akiyama M et al.

Nat Genet

Clinical measurements can be viewed as useful intermediate phenotypes to promote understanding of co...

Total cholesterol levels

128305

Participants

N/A

Studies

Details PubMed

GWAS 2017-10-30

Exome-wide association study of plasma lipids in >300,000 individuals.

Liu DJ, Peloso GM et al.

Nat Genet

We screened variants on an exome-focused genotyping array in >300,000 participants (replication i...

Total cholesterol levels

Replicated

584092

Participants

N/A

Studies

Details PubMed

GWAS 2017-02-21

Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.

Spracklen CN, Chen P et al.

Hum Mol Genet

Large-scale meta-analyses of genome-wide association studies (GWAS) have identified >175 loci ass...

Total cholesterol levels

Replicated

80304

Participants

N/A

Studies

Details PubMed

GWAS 2009-01-16

Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study.

Tanaka T, Shen J et al.

PLoS Genet

Polyunsaturated fatty acids (PUFA) have a role in many physiological processes, including energy pro...

Polyunsaturated fatty acid levels

Replicated

2151

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Population-specific reference panel improves imputation quality for genome-wide association studies conducted on the Japanese population.

Flanagan J, Liu X et al.

Commun Biol

Total cholesterol levels (1KG-JEWEL7K)

2024-12-19

Multi-trait discovery and fine-mapping of lipid loci in 125,000 individuals of African ancestry.

Kamiza AB, Touré SM et al.

Nat Commun

Total cholesterol levels

2023-09-05

Exploring the Genetic Association between Obesity and Serum Lipid Levels Using Bivariate Methods.

Ke J, Gao W et al.

Twin Res Hum Genet

Body mass index and total cholesterol levels

2023-01-06

Dyslipidaemia-Genotype Interactions with Nutrient Intake and Cerebro-Cardiovascular Disease.

Lee SB, Choi JE et al.

Biomedicines

Total cholesterol levels

2022-07-06

Tractor uses local ancestry to enable the inclusion of admixed individuals in GWAS and to boost power.

Atkinson EG, Maihofer AX et al.

Nat Genet

Total cholesterol levels (joint analysis model with African background)

2021-01-18

Heritability and Genome-Wide Association Study of Plasma Cholesterol in Chinese Adult Twins.

Liu H, Wang W et al.

Front Endocrinol (Lausanne)

Total cholesterol levels

2018-11-15

Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.

Kanai M, Akiyama M et al.

Nat Genet

Total cholesterol levels

2018-02-05

Exome-wide association study of plasma lipids in >300,000 individuals.

Liu DJ, Peloso GM et al.

Nat Genet

Total cholesterol levels

2017-10-30

Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.

Spracklen CN, Chen P et al.

Hum Mol Genet

Total cholesterol levels

2017-02-21

Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study.

Tanaka T, Shen J et al.

PLoS Genet

Polyunsaturated fatty acid levels

2009-01-16