Active: Tuberculosis Clear all

GWAS 2024-01-15

Multi-ancestry meta-analysis of host genetic susceptibility to tuberculosis identifies shared genetic architecture.

Schurz H, Naranbhai V et al.

Elife

The heritability of susceptibility to tuberculosis (TB) disease has been well recognized. Over 100 g...

Tuberculosis

33689

Participants

N/A

Studies

Details PubMed

GWAS 2023-03-29

Genome-wide association study of tuberculosis in the western Chinese Han and Tibetan population.

Bai H, Song M et al.

MedComm (2020)

Tuberculosis (TB) remains a serious global public health threat. Accumulated evidence has demonstrat...

Tuberculosis

Replicated

3116

Participants

N/A

Studies

Details PubMed

GWAS 2023-02-01

Genome-wide host-pathogen analyses reveal genetic interaction points in tuberculosis disease.

Phelan J, Gomez-Gonzalez PJ et al.

Nat Commun

The genetics underlying tuberculosis (TB) pathophysiology are poorly understood. Human genome-wide a...

Tuberculosis x mycobacterium tuberculosis lineage interaction

714

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-25

Deciphering Genetic Susceptibility to Tuberculous Meningitis.

Schurz H, Glanzmann B et al.

Front Neurol

Tuberculous meningitis (TBM) is the most severe form of extrapulmonary tuberculosis (TB) that arises...

Tuberculous meningitis vs pulmonary tuberculosis

509

Participants

N/A

Studies

Details PubMed

GWAS 2021-12-03

Resistance to TST/IGRA conversion in Uganda: Heritability and Genome-Wide Association Study.

McHenry ML, Benchek P et al.

EBioMedicine

Pulmonary tuberculosis (TB) is one of the most deadly pathogens on earth. However, the majority of p...

Pulmonary tuberculosis resistance

263

Participants

N/A

Studies

Details PubMed

GWAS 2021-10-15

Local Ancestry Adjusted Allelic Association Analysis Robustly Captures Tuberculosis Susceptibility Loci.

Swart Y, Uren C et al.

Front Genet

Pulmonary tuberculosis (TB), caused by Mycobacterium tuberculosis, is a complex disease. The risk of...

Pulmonary tuberculosis

738

Participants

N/A

Studies

Details PubMed

GWAS 2021-05-28

A next generation sequencing combined genome-wide association study identifies novel tuberculosis susceptibility loci in Chinese population.

Li M, Hu Y et al.

Genomics

The genetic factors of tuberculosis (TB) susceptibility have been widely recognized. Here we perform...

Tuberculosis

Replicated

1209

Participants

N/A

Studies

Details PubMed

GWAS 2021-03-04

Genome-wide association study of resistance to Mycobacterium tuberculosis infection identifies a locus at 10q26.2 in three distinct populations.

Quistrebert J, Orlova M et al.

PLoS Genet

The natural history of tuberculosis (TB) is characterized by a large inter-individual outcome variab...

Resistance to Mycobacterium tuberculosis infection

Replicated

949

Participants

N/A

Studies

Details PubMed

GWAS 2020-11-01

Genetic risk factors in drug-induced liver injury due to isoniazid-containing anti-tuberculosis drug regimens.

Nicoletti P, Devarbhavi H et al.

Clin Pharmacol Ther

Drug-induced liver injury (DILI) is a complication of treatment with antituberculosis (TB) drugs, es...

Drug-induced liver injury (isoniazid-containing anti-tuberculosis drugs)

10467

Participants

N/A

Studies

Details PubMed

GWAS 2019-08-21

Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians.

Luo Y, Suliman S et al.

Nat Commun

Of the 1.8 billion people worldwide infected with Mycobacterium tuberculosis, 5-15% will develop act...

Early progression to active pulmonary tuberculosis in Mycobacterium tuberculosis-infected individuals

3980

Participants

N/A

Studies

Details PubMed

GWAS 2019-05-20

Genome-Wide Association Study Confirming the Association of NAT2 with Susceptibility to Anti-tuberculosis Drug-Induced Liver Injury in Thai Patients.

Suvichapanich S, Wattanapokayakit S et al.

Antimicrob Agents Chemother

Antituberculosis drug-induced liver injury (ATDILI) is a common side effect leading to tuberculosis ...

Liver injury in anti-tuberculosis drug treatment

318

Participants

N/A

Studies

Details PubMed

GWAS 2019-01-18

A Sex-Stratified Genome-Wide Association Study of Tuberculosis Using a Multi-Ethnic Genotyping Array.

Schurz H, Kinnear CJ et al.

Front Genet

Tuberculosis (TB), caused by Mycobacterium tuberculosis, is a complex disease with a known human gen...

Tuberculosis

815

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Multi-ancestry meta-analysis of host genetic susceptibility to tuberculosis identifies shared genetic architecture.

Schurz H, Naranbhai V et al.

Elife

Tuberculosis

2024-01-15

Genome-wide association study of tuberculosis in the western Chinese Han and Tibetan population.

Bai H, Song M et al.

MedComm (2020)

Tuberculosis

2023-03-29

Genome-wide host-pathogen analyses reveal genetic interaction points in tuberculosis disease.

Phelan J, Gomez-Gonzalez PJ et al.

Nat Commun

Tuberculosis x mycobacterium tuberculosis lineage interaction

2023-02-01

Deciphering Genetic Susceptibility to Tuberculous Meningitis.

Schurz H, Glanzmann B et al.

Front Neurol

Tuberculous meningitis vs pulmonary tuberculosis

2022-03-25

Resistance to TST/IGRA conversion in Uganda: Heritability and Genome-Wide Association Study.

McHenry ML, Benchek P et al.

EBioMedicine

Pulmonary tuberculosis resistance

2021-12-03

Local Ancestry Adjusted Allelic Association Analysis Robustly Captures Tuberculosis Susceptibility Loci.

Swart Y, Uren C et al.

Front Genet

Pulmonary tuberculosis

2021-10-15

A next generation sequencing combined genome-wide association study identifies novel tuberculosis susceptibility loci in Chinese population.

Li M, Hu Y et al.

Genomics

Tuberculosis

2021-05-28

Genome-wide association study of resistance to Mycobacterium tuberculosis infection identifies a locus at 10q26.2 in three distinct populations.

Quistrebert J, Orlova M et al.

PLoS Genet

Resistance to Mycobacterium tuberculosis infection

2021-03-04

Genetic risk factors in drug-induced liver injury due to isoniazid-containing anti-tuberculosis drug regimens.

Nicoletti P, Devarbhavi H et al.

Clin Pharmacol Ther

Drug-induced liver injury (isoniazid-containing anti-tuberculosis drugs)

2020-11-01

Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians.

Luo Y, Suliman S et al.

Nat Commun

Early progression to active pulmonary tuberculosis in Mycobacterium tuberculosis-infected individuals

2019-08-21

Genome-Wide Association Study Confirming the Association of NAT2 with Susceptibility to Anti-tuberculosis Drug-Induced Liver Injury in Thai Patients.

Suvichapanich S, Wattanapokayakit S et al.

Antimicrob Agents Chemother

Liver injury in anti-tuberculosis drug treatment

2019-05-20

A Sex-Stratified Genome-Wide Association Study of Tuberculosis Using a Multi-Ethnic Genotyping Array.

Schurz H, Kinnear CJ et al.

Front Genet

Tuberculosis

2019-01-18