Active: Commun Biol Clear all

GWAS 2025-08-29

Efficient candidate drug target discovery through proteogenomics in a Scottish cohort.

Kuliesius J, Timmers PRHJ et al.

Commun Biol

Understanding the genomic basis of human proteomic variability provides powerful tools to probe pote...

E3 ubiquitin-protein ligase pellino homolog 1 protein levels (SomaScan ID:10758-2)

194

Participants

N/A

Studies

Details PubMed

GWAS 2025-04-05

Trans-ethnic GWAS meta-analysis of idiopathic spermatogenic failure highlights the immune-mediated nature of Sertoli cell-only syndrome.

González-Muñoz S, Long Y et al.

Commun Biol

Non-obstructive azoospermia, a severe form of male infertility caused by spermatogenic failure (SPGF...

Spermatogenic failure

5863

Participants

N/A

Studies

Details PubMed

GWAS 2025-03-01

Exome sequencing identifies novel genes associated with cerebellar volume and microstructure.

Liang Y, Ma D et al.

Commun Biol

Proteins encoded by exons are critical for cellular functions, and mutations in these genes often re...

Superior cerebellar peduncle fractional anisotropy

35412

Participants

N/A

Studies

Details PubMed

GWAS 2025-01-10

The genomic architecture of circulating cytokine levels points to drug targets for immune-related diseases.

Konieczny MJ, Omarov M et al.

Commun Biol

Circulating cytokines orchestrate immune reactions and are promising drug targets for immune-mediate...

CCL2 protein levels

74783

Participants

N/A

Studies

Details PubMed

GWAS 2024-12-19

Population-specific reference panel improves imputation quality for genome-wide association studies conducted on the Japanese population.

Flanagan J, Liu X et al.

Commun Biol

To improve imputation quality for genome-wide association studies (GWAS) conducted on the Japanese p...

Total cholesterol levels (1KG-JEWEL7K)

181927

Participants

N/A

Studies

Details PubMed

GWAS 2024-12-06

Novel loci and biomedical consequences of iron homoeostasis variation.

Allara E, Bell S et al.

Commun Biol

Iron homoeostasis is tightly regulated, with hepcidin and soluble transferrin receptor (sTfR) playin...

Hepcidin concentration

91675

Participants

N/A

Studies

Details PubMed

GWAS 2024-09-30

Genome-wide association studies for pelvic organ prolapse in the Japanese population.

Matsunami M, Imamura M et al.

Commun Biol

Pelvic organ prolapse (POP) affects approximately 40% of elderly women, characterized by the descent...

Pelvic organ prolapse

77396

Participants

N/A

Studies

Details PubMed

GWAS 2024-09-28

Imaging genetics of language network functional connectivity reveals links with language-related abilities, dyslexia and handedness.

Amelink JS, Postema MC et al.

Commun Biol

Language is supported by a distributed network of brain regions with a particular contribution from ...

Brain language network hemispheric differences in intrahemispheric functional connectivity

29681

Participants

N/A

Studies

Details PubMed

GWAS 2024-09-09

Genome-wide association study meta-analysis of neurofilament light (NfL) levels in blood reveals novel loci related to neurodegeneration.

Ahmad S, Imtiaz MA et al.

Commun Biol

Neurofilament light chain (NfL) levels in circulation have been established as a sensitive biomarker...

Neurofilament light chain levels

18532

Participants

N/A

Studies

Details PubMed

GWAS 2024-09-05

A genome-wide association study of occupational creativity and its relations with well-being and career success.

Li WD, Zhang X et al.

Commun Biol

Creativity is one defining characteristic of human species. There have been mixed findings on how cr...

Occupational creativity

Replicated

152778

Participants

N/A

Studies

Details PubMed

GWAS 2024-08-22

A genome-wide association study identifies novel loci of vertigo in an Asian population-based cohort.

Chen SP, Hsu CL et al.

Commun Biol

The contributing genetic factors of vertigo remain poorly characterized, particularly in individuals...

Vertigo

60786

Participants

N/A

Studies

Details PubMed

GWAS 2024-05-20

A genome-wide association study identifies a locus associated with knee extension strength in older Japanese individuals.

Ito S, Takuwa H et al.

Commun Biol

Sarcopenia is a common skeletal muscle disease in older people. Lower limb muscle strength is a good...

Knee extension strength

3452

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Efficient candidate drug target discovery through proteogenomics in a Scottish cohort.

Kuliesius J, Timmers PRHJ et al.

Commun Biol

E3 ubiquitin-protein ligase pellino homolog 1 protein levels (SomaScan ID:10758-2)

2025-08-29

Trans-ethnic GWAS meta-analysis of idiopathic spermatogenic failure highlights the immune-mediated nature of Sertoli cell-only syndrome.

González-Muñoz S, Long Y et al.

Commun Biol

Spermatogenic failure

2025-04-05

Exome sequencing identifies novel genes associated with cerebellar volume and microstructure.

Liang Y, Ma D et al.

Commun Biol

Superior cerebellar peduncle fractional anisotropy

2025-03-01

The genomic architecture of circulating cytokine levels points to drug targets for immune-related diseases.

Konieczny MJ, Omarov M et al.

Commun Biol

CCL2 protein levels

2025-01-10

Population-specific reference panel improves imputation quality for genome-wide association studies conducted on the Japanese population.

Flanagan J, Liu X et al.

Commun Biol

Total cholesterol levels (1KG-JEWEL7K)

2024-12-19

Novel loci and biomedical consequences of iron homoeostasis variation.

Allara E, Bell S et al.

Commun Biol

Hepcidin concentration

2024-12-06

Genome-wide association studies for pelvic organ prolapse in the Japanese population.

Matsunami M, Imamura M et al.

Commun Biol

Pelvic organ prolapse

2024-09-30

Imaging genetics of language network functional connectivity reveals links with language-related abilities, dyslexia and handedness.

Amelink JS, Postema MC et al.

Commun Biol

Brain language network hemispheric differences in intrahemispheric functional connectivity

2024-09-28

Genome-wide association study meta-analysis of neurofilament light (NfL) levels in blood reveals novel loci related to neurodegeneration.

Ahmad S, Imtiaz MA et al.

Commun Biol

Neurofilament light chain levels

2024-09-09

A genome-wide association study of occupational creativity and its relations with well-being and career success.

Li WD, Zhang X et al.

Commun Biol

Occupational creativity

2024-09-05

A genome-wide association study identifies novel loci of vertigo in an Asian population-based cohort.

Chen SP, Hsu CL et al.

Commun Biol

Vertigo

2024-08-22

A genome-wide association study identifies a locus associated with knee extension strength in older Japanese individuals.

Ito S, Takuwa H et al.

Commun Biol

Knee extension strength

2024-05-20