Active: J Hum Genet Clear all

GWAS 2024-08-15

The genetic architecture of age at menarche and its causal effects on other traits.

Feng GJ, Xu Q et al.

J Hum Genet

Age at menarche (AAM) is a sign of puberty of females. It is a heritable trait associated with vario...

Age at menarche

371060

Participants

N/A

Studies

Details PubMed

GWAS 2024-05-07

Exploring the relationship between admixture and genetic susceptibility to attention deficit hyperactivity disorder in two Latin American cohorts.

Garzón Rodríguez N, Briceño-Balcázar I et al.

J Hum Genet

Contemporary research on the genomics of Attention Deficit Hyperactivity Disorder (ADHD) often under...

Attention deficit hyperactivity disorder

546

Participants

N/A

Studies

Details PubMed

GWAS 2023-06-26

Genome-wide association study identifies novel susceptibilities to adult moyamoya disease.

Jeon JP, Hong EP et al.

J Hum Genet

Genome-wide association study has limited to discover single-nucleotide polymorphisms (SNPs) in seve...

Moyamoya disease

512

Participants

N/A

Studies

Details PubMed

GWAS 2023-04-18

Common and rare variants associated with cardiometabolic traits across 98,622 whole-genome sequences in the All of Us research program.

Wang X, Ryu J et al.

J Hum Genet

All of Us is a biorepository aiming to advance biomedical research by providing various types of dat...

Atrial fibrillation

98564

Participants

N/A

Studies

Details PubMed

GWAS 2023-01-30

Genome-wide association study of age at menarche in the Taiwan Biobank suggests NOL4 as a novel associated gene.

Tsai MC, Hsu CH et al.

J Hum Genet

Sexual maturation is a complex physiological process that involves multiple variables, such as genet...

Age at menarche

39827

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-30

Genome-wide association study of primary dysmenorrhea in the Taiwan Biobank validates associations near the NGF and IL1 gene loci.

Lee CC, Lee MG et al.

J Hum Genet

Using the Taiwan Biobank, we aimed to identify traits and genetic variations that could predispose H...

Primary dysmenorrhea

25206

Participants

N/A

Studies

Details PubMed

GWAS 2022-03-07

Genome-wide association study identifies APOE locus influencing plasma p-tau181 levels.

Huang YY, Yang YX et al.

J Hum Genet

As a promising diagnostic and prognostic biomarker for Alzheimer's Disease (AD), plasma p-tau181 is ...

Plasma p-tau181 levels in non-dementia individuals

671

Participants

N/A

Studies

Details PubMed

GWAS 2022-01-11

Host genetic factors of COVID-19 susceptibility and disease severity in a Thai population.

Chamnanphon M, Pongpanich M et al.

J Hum Genet

Host genetic factors have been shown to play a role in SARs-CoV-2 infection in diverse populations. ...

COVID-19

222

Participants

N/A

Studies

Details PubMed

GWAS 2021-11-01

Genome-wide meta-analysis revealed several genetic loci associated with serum uric acid levels in Korean population: an analysis of Korea Biobank data.

Park JS, Kim Y et al.

J Hum Genet

The serum uric acid (SUA) level is an important determinant of gout, hypertension, metabolic syndrom...

Serum uric acid levels

60585

Participants

N/A

Studies

Details PubMed

GWAS 2021-10-21

Genome-wide association study of colorectal polyps identified highly overlapping polygenic architecture with colorectal cancer.

Hikino K, Koido M et al.

J Hum Genet

No genome-wide association studies (GWAS) were reported for colorectal polyps and the overlap in pol...

Colorectal cancer

87609

Participants

N/A

Studies

Details PubMed

GWAS 2021-08-11

Analyses of biomarker traits in diverse UK biobank participants identify associations missed by European-centric analysis strategies.

Sun Q, Graff M et al.

J Hum Genet

Despite the dramatic underrepresentation of non-European populations in human genetics studies, rese...

Serum alkaline phosphatase levels

Replicated

2559

Participants

N/A

Studies

Details PubMed

GWAS 2021-01-20

Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease.

Crawford AA, Bankier S et al.

J Hum Genet

The stress hormone cortisol modulates fuel metabolism, cardiovascular homoeostasis, mood, inflammati...

Plasma cortisol levels (morning)

25314

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

The genetic architecture of age at menarche and its causal effects on other traits.

Feng GJ, Xu Q et al.

J Hum Genet

Age at menarche

2024-08-15

Exploring the relationship between admixture and genetic susceptibility to attention deficit hyperactivity disorder in two Latin American cohorts.

Garzón Rodríguez N, Briceño-Balcázar I et al.

J Hum Genet

Attention deficit hyperactivity disorder

2024-05-07

Genome-wide association study identifies novel susceptibilities to adult moyamoya disease.

Jeon JP, Hong EP et al.

J Hum Genet

Moyamoya disease

2023-06-26

Common and rare variants associated with cardiometabolic traits across 98,622 whole-genome sequences in the All of Us research program.

Wang X, Ryu J et al.

J Hum Genet

Atrial fibrillation

2023-04-18

Genome-wide association study of age at menarche in the Taiwan Biobank suggests NOL4 as a novel associated gene.

Tsai MC, Hsu CH et al.

J Hum Genet

Age at menarche

2023-01-30

Genome-wide association study of primary dysmenorrhea in the Taiwan Biobank validates associations near the NGF and IL1 gene loci.

Lee CC, Lee MG et al.

J Hum Genet

Primary dysmenorrhea

2022-03-30

Genome-wide association study identifies APOE locus influencing plasma p-tau181 levels.

Huang YY, Yang YX et al.

J Hum Genet

Plasma p-tau181 levels in non-dementia individuals

2022-03-07

Host genetic factors of COVID-19 susceptibility and disease severity in a Thai population.

Chamnanphon M, Pongpanich M et al.

J Hum Genet

COVID-19

2022-01-11

Genome-wide meta-analysis revealed several genetic loci associated with serum uric acid levels in Korean population: an analysis of Korea Biobank data.

Park JS, Kim Y et al.

J Hum Genet

Serum uric acid levels

2021-11-01

Genome-wide association study of colorectal polyps identified highly overlapping polygenic architecture with colorectal cancer.

Hikino K, Koido M et al.

J Hum Genet

Colorectal cancer

2021-10-21

Analyses of biomarker traits in diverse UK biobank participants identify associations missed by European-centric analysis strategies.

Sun Q, Graff M et al.

J Hum Genet

Serum alkaline phosphatase levels

2021-08-11

Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease.

Crawford AA, Bankier S et al.

J Hum Genet

Plasma cortisol levels (morning)

2021-01-20