Active: Kidney Int Clear all

GWAS 2025-10-10

Genetic screens of imaging-derived kidney volumes identify genes linked to kidney function.

Monteiro-Martins S, Li Y et al.

Kidney Int

Introduction: Chronic kidney disease (CKD) is defined as sustained abnormalities in kidney function ...

Kidney volume

38816

Participants

N/A

Studies

Details PubMed

GWAS 2022-07-21

Identification of 969 protein quantitative trait loci in an African American population with kidney disease attributed to hypertension.

Surapaneni A, Schlosser P et al.

Kidney Int

Investigations into the causal underpinnings of disease processes can be aided by the incorporation ...

Carnitine O-acetyltransferase level in Chronic kidney disease with hypertension and no diabetes (12637_7)

466

Participants

N/A

Studies

Details PubMed

GWAS 2022-02-01

Trans-ethnic genome-wide association study of blood metabolites in the chronic renal insufficiency cohort (CRIC) study.

Rhee EP, Surapaneni A et al.

Kidney Int

Metabolomics genome wide association study (GWAS) help outline the genetic contribution to human met...

Imidazole propionate levels in chronic kidney disease

822

Participants

N/A

Studies

Details PubMed

GWAS 2021-06-28

A genome-wide association study suggests correlations of common genetic variants with peritoneal solute transfer rates in patients with kidney failure receiving peritoneal dialysis.

Mehrotra R, Stanaway IB et al.

Kidney Int

Movement of solutes across the peritoneum allows for the use of peritoneal dialysis to treat kidney ...

Peritoneal solute transfer rates in kidney failure treated with peritoneal dialysis

2212

Participants

N/A

Studies

Details PubMed

GWAS 2021-04-07

Genome-wide association study of serum metabolites in the African American Study of Kidney Disease and Hypertension.

Luo S, Feofanova EV et al.

Kidney Int

The genome-wide association study (GWAS) is a powerful means to study genetic determinants of diseas...

Serum metabolite concentrations in chronic kidney disease

619

Participants

N/A

Studies

Details PubMed

GWAS 2020-10-30

Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline.

Gorski M, Jung B et al.

Kidney Int

Rapid decline of glomerular filtration rate estimated from creatinine (eGFRcrea) is associated with ...

Estimated glomerular filtration rate (creatinine, Rapid3)

141964

Participants

N/A

Studies

Details PubMed

GWAS 2020-06-14

Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome.

Jia X, Yamamura T et al.

Kidney Int

To understand the genetics of steroid-sensitive nephrotic syndrome (SSNS), we conducted a genome-wid...

Childhood steroid-sensitive nephrotic syndrome

Replicated

64929

Participants

N/A

Studies

Details PubMed

GWAS 2019-03-12

Identification of 22 novel loci associated with urinary biomarkers of albumin, sodium, and potassium excretion.

Zanetti D, Rao A et al.

Kidney Int

Urine biomarkers reflecting kidney function and handling of dietary sodium and potassium are strongl...

Urinary albumin-to-creatinine ratio

Replicated

328289

Participants

N/A

Studies

Details PubMed

GWAS 2018-06-06

Genome-wide association studies suggest that APOL1-environment interactions more likely trigger kidney disease in African Americans with nondiabetic nephropathy than strong APOL1-second gene interactions.

Langefeld CD, Comeau ME et al.

Kidney Int

African Americans carrying two apolipoprotein L1 gene (APOL1) renal risk variants have a high risk f...

End stage renal disease x APOL1 genotype interaction

2649

Participants

N/A

Studies

Details PubMed

GWAS 2015-06-17

Genome-wide association study of acute kidney injury after coronary bypass graft surgery identifies susceptibility loci.

Stafford-Smith M, Li YJ et al.

Kidney Int

Acute kidney injury (AKI) is a common, serious complication of cardiac surgery. Since prior studies ...

Acute kidney injury in coronary artery bypass surgery (creatinine rise)

Replicated

1253

Participants

N/A

Studies

Details PubMed

GWAS 2014-12-10

Genome-wide association study of kidney function decline in individuals of European descent.

Gorski M, Tin A et al.

Kidney Int

Genome-wide association studies (GWASs) have identified multiple loci associated with cross-sectiona...

Kidney function decline traits

Replicated

63558

Participants

N/A

Studies

Details PubMed

GWAS 2010-12-08

A genome-wide association study for diabetic nephropathy genes in African Americans.

McDonough CW, Palmer ND et al.

Kidney Int

A genome-wide association study was performed using the Affymetrix 6.0 chip to identify genes associ...

Type 2 diabetes nephropathy

Replicated

3393

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Genetic screens of imaging-derived kidney volumes identify genes linked to kidney function.

Monteiro-Martins S, Li Y et al.

Kidney Int

Kidney volume

2025-10-10

Identification of 969 protein quantitative trait loci in an African American population with kidney disease attributed to hypertension.

Surapaneni A, Schlosser P et al.

Kidney Int

Carnitine O-acetyltransferase level in Chronic kidney disease with hypertension and no diabetes (12637_7)

2022-07-21

Trans-ethnic genome-wide association study of blood metabolites in the chronic renal insufficiency cohort (CRIC) study.

Rhee EP, Surapaneni A et al.

Kidney Int

Imidazole propionate levels in chronic kidney disease

2022-02-01

A genome-wide association study suggests correlations of common genetic variants with peritoneal solute transfer rates in patients with kidney failure receiving peritoneal dialysis.

Mehrotra R, Stanaway IB et al.

Kidney Int

Peritoneal solute transfer rates in kidney failure treated with peritoneal dialysis

2021-06-28

Genome-wide association study of serum metabolites in the African American Study of Kidney Disease and Hypertension.

Luo S, Feofanova EV et al.

Kidney Int

Serum metabolite concentrations in chronic kidney disease

2021-04-07

Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline.

Gorski M, Jung B et al.

Kidney Int

Estimated glomerular filtration rate (creatinine, Rapid3)

2020-10-30

Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome.

Jia X, Yamamura T et al.

Kidney Int

Childhood steroid-sensitive nephrotic syndrome

2020-06-14

Identification of 22 novel loci associated with urinary biomarkers of albumin, sodium, and potassium excretion.

Zanetti D, Rao A et al.

Kidney Int

Urinary albumin-to-creatinine ratio

2019-03-12

Genome-wide association studies suggest that APOL1-environment interactions more likely trigger kidney disease in African Americans with nondiabetic nephropathy than strong APOL1-second gene interactions.

Langefeld CD, Comeau ME et al.

Kidney Int

End stage renal disease x APOL1 genotype interaction

2018-06-06

Genome-wide association study of acute kidney injury after coronary bypass graft surgery identifies susceptibility loci.

Stafford-Smith M, Li YJ et al.

Kidney Int

Acute kidney injury in coronary artery bypass surgery (creatinine rise)

2015-06-17

Genome-wide association study of kidney function decline in individuals of European descent.

Gorski M, Tin A et al.

Kidney Int

Kidney function decline traits

2014-12-10

A genome-wide association study for diabetic nephropathy genes in African Americans.

McDonough CW, Palmer ND et al.

Kidney Int

Type 2 diabetes nephropathy

2010-12-08