Health & Traits Publications

Hou L, Heilbronner U et al.

Lancet

Lithium is a first-line treatment in bipolar disorder, but individual response is variable. Previous...

Response to lithium treatment in bipolar disorder (dichotomous phenotype)

Cleynen I, Boucher G et al.

Lancet

Crohn's disease and ulcerative colitis are the two major forms of inflammatory bowel disease; treatm...

Inflammatory bowel disease

Perera MA, Cavallari LH et al.

Lancet

VKORC1 and CYP2C9 are important contributors to warfarin dose variability, but explain less variabil...

Warfarin maintenance dose

Smoller JW

Lancet

Findings from family and twin studies suggest that genetic contributions to psychiatric disorders do...

Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined)

Zeggini E, Panoutsopoulou K et al.

Lancet

Osteoarthritis is the most common form of arthritis worldwide and is a major cause of pain and disab...

Osteoarthritis

Ferreira MA, Matheson MC et al.

Lancet

We aimed to identify novel genetic variants affecting asthma risk, since these might provide novel i...

Asthma

Nalls MA, Plagnol V et al.

Lancet

Genome-wide association studies (GWAS) for Parkinson's disease have linked two loci (MAPT and SNCA) ...

Parkinson's disease

Reilly MP, Li M et al.

Lancet

We tested whether genetic factors distinctly contribute to either development of coronary atheroscle...

Coronary artery disease

Wang TJ, Zhang F et al.

Lancet

Vitamin D is crucial for maintenance of musculoskeletal health, and might also have a role in extras...

Vitamin D insufficiency

Dehghan A, Köttgen A et al.

Lancet

Hyperuricaemia, a highly heritable trait, is a key risk factor for gout. We aimed to identify novel ...

Urate levels

Richards JB, Rivadeneira F et al.

Lancet

Osteoporosis is diagnosed by the measurement of bone mineral density, which is a highly heritable an...

Bone mineral density

Sandhu MS, Waterworth DM et al.

Lancet

LDL cholesterol has a causal role in the development of cardiovascular disease. Improved understandi...

LDL cholesterol