LDL-cholesterol concentrations: a genome-wide association study.
Sandhu MS, Waterworth DM, Debenham SL et al.
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Abstract
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LDL cholesterol has a causal role in the development of cardiovascular disease. Improved understanding of the biological mechanisms that underlie the metabolism and regulation of LDL cholesterol might help to identify novel therapeutic targets. We therefore did a genome-wide association study of LDL-cholesterol concentrations.
11,685 European ancestry individuals
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