Active: Lancet Neurol Clear all

GWAS 2023-08-23

Identification of genetic risk loci and causal insights associated with Parkinson's disease in African and African admixed populations: a genome-wide association study.

Rizig M, Bandres-Ciga S et al.

Lancet Neurol

An understanding of the genetic mechanisms underlying diseases in ancestrally diverse populations is...

Parkinson's disease

197918

Participants

N/A

Studies

Details PubMed

GWAS 2021-03-25

Genetic basis of lacunar stroke: a pooled analysis of individual patient data and genome-wide association studies.

Traylor M, Persyn E et al.

Lancet Neurol

The genetic basis of lacunar stroke is poorly understood, with a single locus on 16q24 identified to...

Lacunar stroke

225419

Participants

N/A

Studies

Details PubMed

GWAS 2020-12-17

Genetic determinants of survival in progressive supranuclear palsy: a genome-wide association study.

Jabbari E, Koga S et al.

Lancet Neurol

The genetic basis of variation in the progression of primary tauopathies has not been determined. We...

Survival in progressive supranuclear palsy

Replicated

1416

Participants

N/A

Studies

Details PubMed

GWAS 2020-09-16

Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study.

Jones E, Hummerich H et al.

Lancet Neurol

Human prion diseases are rare and usually rapidly fatal neurodegenerative disorders, the most common...

Creutzfeldt-Jakob disease (sporadic)

Replicated

516793

Participants

N/A

Studies

Details PubMed

GWAS 2019-12-01

Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies.

Nalls MA, Blauwendraat C et al.

Lancet Neurol

Genome-wide association studies (GWAS) in Parkinson's disease have increased the scope of biological...

Parkinson's disease or first degree relation to individual with Parkinson's disease

Replicated

1474097

Participants

N/A

Studies

Details PubMed

GWAS 2018-04-30

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.

Pottier C, Zhou X et al.

Lancet Neurol

Loss-of-function mutations in GRN cause frontotemporal lobar degeneration (FTLD). Patients with GRN ...

Behavioural changes in frontotemporal lobe dementia

Replicated

382

Participants

N/A

Studies

Details PubMed

GWAS 2018-01-01

Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study.

Guerreiro R, Ross OA et al.

Lancet Neurol

Dementia with Lewy bodies is the second most common form of dementia in elderly people but has been ...

Dementia with Lewy bodies

Replicated

6197

Participants

N/A

Studies

Details PubMed

GWAS 2017-11-01

Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis.

Schormair B, Zhao C et al.

Lancet Neurol

Restless legs syndrome is a prevalent chronic neurological disorder with potentially severe mental a...

Restless legs syndrome

Replicated

428534

Participants

N/A

Studies

Details PubMed

GWAS 2017-06-20

Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study.

Moss DJH, Pardiñas AF et al.

Lancet Neurol

Huntington's disease is caused by a CAG repeat expansion in the huntingtin gene, HTT. Age at onset h...

Huntington's disease progression

1989

Participants

N/A

Studies

Details PubMed

GWAS 2016-04-07

Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies.

Chauhan G

Lancet Neurol

Genetic determinants of stroke, the leading neurological cause of death and disability, are poorly u...

Ischemic stroke

Replicated

152433

Participants

N/A

Studies

Details PubMed

GWAS 2015-12-18

Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study.

Pulit SL

Lancet Neurol

The discovery of disease-associated loci through genome-wide association studies (GWAS) is the leadi...

Ischemic stroke

Replicated

432920

Participants

N/A

Studies

Details PubMed

GWAS 2014-07-30

Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies.

Anney RJ

Lancet Neurol

The epilepsies are a clinically heterogeneous group of neurological disorders. Despite strong eviden...

Epilepsy

34853

Participants

N/A

Studies

Details PubMed

Title

Author

Journal

Disease/Trait

Date

Actions

Identification of genetic risk loci and causal insights associated with Parkinson's disease in African and African admixed populations: a genome-wide association study.

Rizig M, Bandres-Ciga S et al.

Lancet Neurol

Parkinson's disease

2023-08-23

Genetic basis of lacunar stroke: a pooled analysis of individual patient data and genome-wide association studies.

Traylor M, Persyn E et al.

Lancet Neurol

Lacunar stroke

2021-03-25

Genetic determinants of survival in progressive supranuclear palsy: a genome-wide association study.

Jabbari E, Koga S et al.

Lancet Neurol

Survival in progressive supranuclear palsy

2020-12-17

Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study.

Jones E, Hummerich H et al.

Lancet Neurol

Creutzfeldt-Jakob disease (sporadic)

2020-09-16

Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies.

Nalls MA, Blauwendraat C et al.

Lancet Neurol

Parkinson's disease or first degree relation to individual with Parkinson's disease

2019-12-01

Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.

Pottier C, Zhou X et al.

Lancet Neurol

Behavioural changes in frontotemporal lobe dementia

2018-04-30

Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study.

Guerreiro R, Ross OA et al.

Lancet Neurol

Dementia with Lewy bodies

2018-01-01

Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis.

Schormair B, Zhao C et al.

Lancet Neurol

Restless legs syndrome

2017-11-01

Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study.

Moss DJH, Pardiñas AF et al.

Lancet Neurol

Huntington's disease progression

2017-06-20

Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies.

Chauhan G

Lancet Neurol

Ischemic stroke

2016-04-07

Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study.

Pulit SL

Lancet Neurol

Ischemic stroke

2015-12-18

Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies.

Anney RJ

Lancet Neurol

Epilepsy

2014-07-30