Genomewide association analysis followed by a replication study implicates a novel candidate gene for neuroticism.
van den Oord EJ, Kuo PH, Hartmann AM et al.
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Abstract
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Context: Neuroticism is a trait that reflects a tendency toward negative mood states. It has long been linked to internalizing psychiatric conditions, such as anxiety and depression, and it accounts for much of the substantial comorbidity seen between these disorders.
1,227 European ancestry individuals
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