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GWAS Study

Genome-wide association scan for diabetic nephropathy susceptibility genes in type 1 diabetes.

Pezzolesi MG, Poznik GD, Mychaleckyj JC et al.

19252134 PubMed ID
GWAS Study Type
3009 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

PM
Pezzolesi MG
PG
Poznik GD
MJ
Mychaleckyj JC
PA
Paterson AD
BM
Barati MT
KJ
Klein JB
ND
Ng DP
PG
Placha G
CL
Canani LH
BJ
Bochenski J
WD
Waggott D
MM
Merchant ML
KB
Krolewski B
ML
Mirea L
WK
Wanic K
KP
Katavetin P
KM
Kure M
WP
Wolkow P
DJ
Dunn JS
SA
Smiles A
WW
Walker WH
BA
Boright AP
BS
Bull SB
DA
Doria A
RJ
Rogus JJ
RS
Rich SS
WJ
Warram JH
KA
Krolewski AS
Chapter II

Abstract

Summary of the research findings

Objective: Despite extensive evidence for genetic susceptibility to diabetic nephropathy, the identification of susceptibility genes and their variants has had limited success. To search for genes that contribute to diabetic nephropathy, a genome-wide association scan was implemented on the Genetics of Kidneys in Diabetes collection.

820 European ancestry cases, 885 European ancestry controls

Chapter III

Study Statistics

Key metrics and study information

3009
Total Participants
GWAS
Study Type
Yes
Replicated
1,304 European ancestry individuals
Replication Participants
European
Ancestry
U.S., Canada
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

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