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GWAS Study

Genome-wide association study of alcohol dependence implicates a region on chromosome 11.

Edenberg HJ, Koller DL, Xuei X et al.

20201924 PubMed ID
GWAS Study Type
2146 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

EH
Edenberg HJ
KD
Koller DL
XX
Xuei X
WL
Wetherill L
MJ
McClintick JN
AL
Almasy L
BL
Bierut LJ
BK
Bucholz KK
GA
Goate A
AF
Aliev F
DD
Dick D
HV
Hesselbrock V
HA
Hinrichs A
KJ
Kramer J
KS
Kuperman S
NJ
Nurnberger JI
RJ
Rice JP
SM
Schuckit MA
TR
Taylor R
TW
Todd Webb B
TJ
Tischfield JA
PB
Porjesz B
FT
Foroud T
Chapter II

Abstract

Summary of the research findings

Alcohol dependence is a complex disease, and although linkage and candidate gene studies have identified several genes associated with the risk for alcoholism, these explain only a portion of the risk.

847 European ancestry cases, 552 European ancestry controls, 345 African American cases, 140 African American controls

Chapter III

Study Statistics

Key metrics and study information

2146
Total Participants
GWAS
Study Type
Yes
Replicated
262 families
Replication Participants
African American or Afro-Caribbean, European
Ancestry
U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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Analysis In Progress

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