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GWAS Study

Genome-wide association study implicates PARD3B-based AIDS restriction.

Troyer JL, Nelson GW, Lautenberger JA et al.

21502085 PubMed ID
GWAS Study Type
755 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

TJ
Troyer JL
NG
Nelson GW
LJ
Lautenberger JA
CL
Chinn L
MC
McIntosh C
JR
Johnson RC
SE
Sezgin E
KB
Kessing B
MM
Malasky M
HS
Hendrickson SL
LG
Li G
PJ
Pontius J
TM
Tang M
AP
An P
WC
Winkler CA
LS
Limou S
LC
Le Clerc S
DO
Delaneau O
ZJ
Zagury JF
SH
Schuitemaker H
VM
van Manen D
BJ
Bream JH
GE
Gomperts ED
BS
Buchbinder S
GJ
Goedert JJ
KG
Kirk GD
OS
O'Brien SJ
Chapter II

Abstract

Summary of the research findings

Host genetic variation influences human immunodeficiency virus (HIV) infection and progression to AIDS. Here we used clinically well-characterized subjects from 5 pretreatment HIV/AIDS cohorts for a genome-wide association study to identify gene associations with rate of AIDS progression.

755 European ancestry seroconverter cases

Chapter III

Study Statistics

Key metrics and study information

755
Total Participants
GWAS
Study Type
No
Replicated
European
Ancestry
U.S.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

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