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GWAS Study

A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study.

Granada M, Wilk JB, Tuzova M et al.

22075330 PubMed ID
GWAS Study Type
14628 Participants
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Chapter I

Publication Details

Comprehensive information about this research publication

Authors

GM
Granada M
WJ
Wilk JB
TM
Tuzova M
SD
Strachan DP
WS
Weidinger S
AE
Albrecht E
GC
Gieger C
HJ
Heinrich J
HB
Himes BE
HG
Hunninghake GM
CJ
Celedón JC
WS
Weiss ST
CW
Cruikshank WW
FL
Farrer LA
CD
Center DM
OG
O'Connor GT
Chapter II

Abstract

Summary of the research findings

Atopy and plasma IgE concentration are genetically complex traits, and the specific genetic risk factors that lead to IgE dysregulation and clinical atopy are an area of active investigation.

6,819 European ancestry individuals

Chapter III

Study Statistics

Key metrics and study information

14628
Total Participants
GWAS
Study Type
Yes
Replicated
7,809 European ancestry indivduals
Replication Participants
European
Ancestry
U.S., Germany, U.K.
Recruitment Country
Chapter IV

Analysis

Comprehensive review of health and genetic findings

Important Disclaimer: This review has been performed semi-automatically and is provided for informational purposes only. While we strive for accuracy, this analysis may contain errors, omissions, or misinterpretations of the original research. DNA Genics disclaims all liability for any inaccuracies, errors, or consequences arising from the use of this information. Users should independently verify all information and consult original research publications before making any decisions based on this content. This analysis is not intended as a substitute for professional scientific review or medical advice.

Analysis In Progress

Our analysis of this publication is currently being prepared. Please check back soon for comprehensive insights into the health and genetic findings discussed in this research.